| 基因名 | 疾病 | 靶向药 | 化疗药 | 基因突变 | 临床解释 |
|---|---|---|---|---|---|
| DOCK7 | 0 | 0 | |||
| DOCK2 | 0 | 0 | |||
| DOCK11 | 0 | 0 | |||
| DNTT | 0 | 0 | |||
| DNMT3B | 0 | 0 | |||
| DNMT3A | 急性白血病,急性髓系白血病,癌症,骨髓增生异常综合征,T细胞急性淋巴细胞白血病 | 阿特朱单抗，阿替利珠单抗,Decitabine,纳武单抗（纳武利尤单抗）,派姆单抗（帕博利珠单抗）, | 柔红霉素,伊达比星, | 4 | 37 |
| DNMT1 | 胃腺癌,卵巢癌 | Decitabine, | 顺铂, | 1 | 2 |
| DNM2 | 0 | 0 | |||
| DNAJC19 | 0 | 0 | |||
| DNAJC11 | 0 | 0 | |||
| DNAJB1 | 0 | 0 | |||
| DNAH6 | 0 | 0 | |||
| DNAH1 | 0 | 0 | |||
| DMD | 0 | 0 | |||
| DMC1 | 0 | 0 | |||
| DLL3 | 小细胞肺癌 | Rova-T, | 1 | 1 | |
| DLC1 | 0 | 0 | |||
| DLAT | 0 | 0 | |||
| DKK1 | 结直肠癌 | L-Folinic Acid, | 氟尿嘧啶,伊立替康,奥沙利铂, | 1 | 1 |
| DIS3L2 | 0 | 0 | |||
| DIS3 | 0 | 0 | |||
| DIRAS3 | 0 | 0 | |||
| DICER1 | 腺型卵巢卵黄囊肿瘤,恶性舍托利-莱迪格细胞瘤,卵巢癌,卵巢颗粒细胞瘤,胸膜肺母细胞瘤 | 12 | 18 | ||
| DIAPH1 | 0 | 0 | |||
| DHX9 | 0 | 0 | |||
| DHX35 | 0 | 0 | |||
| DHFR | 0 | 0 | |||
| DGKH | 小儿B细胞急性淋巴细胞白血病 | 1 | 1 | ||
| DEPDC5 | 0 | 0 | |||
| DENND1A | 0 | 0 | |||
| DEK | 头颈癌 | 派姆单抗（帕博利珠单抗）, | 1 | 1 | |
| DEFA1 | 前列腺癌 | 多西他赛, | 1 | 1 | |
| DDX5 | 0 | 0 | |||
| DDX43 | 葡萄膜黑色素瘤 | PD0325901,司美替尼,曲美替尼, | 1 | 1 | |
| DDX41 | 血液癌 | 1 | 1 | ||
| DDX3X | 0 | 0 | |||
| DDR2 | 非小细胞肺癌 | 达沙替尼,厄洛替尼, | 7 | 7 | |
| DDR1 | 0 | 0 | |||
| DDIT3 | 黏液样脂肪肉瘤 | NVP-AEW541, | 2 | 3 | |
| DDB2 | 0 | 0 | |||
| DDB1 | 0 | 0 | |||
| DCUN1D1 | 0 | 0 | |||
| DCLRE1C | 0 | 0 | |||
| DCK | 0 | 0 | |||
| DCC | 结直肠癌 | 1 | 1 | ||
| DCBLD1 | 0 | 0 | |||
| DCAF4L2 | 0 | 0 | |||
| DCAF12L2 | 0 | 0 | |||
| DCAF12L1 | 0 | 0 | |||
| DBT | 0 | 0 | |||
| DAXX | 0 | 0 | |||
| DAPK1 | 0 | 0 | |||
| CYSLTR2 | 0 | 0 | |||
| CYP4B1 | 0 | 0 | |||
| CYP3A5 | 0 | 0 | |||
| Cyp3a44 | 0 | 0 | |||
| CYP3A4 | 0 | 0 | |||
| CYP2E1 | 0 | 0 | |||
| CYP2D6 | 乳腺癌 | 1 | 1 | ||
| CYP2C93 | 0 | 0 | |||
| CYP2C9 | 0 | 0 | |||
| CYP2C8 | 0 | 0 | |||
| CYP2C192 | 0 | 0 | |||
| CYP2C19 | 0 | 0 | |||
| CYP2B66 | 0 | 0 | |||
| CYP2B6 | 0 | 0 | |||
| CYP2A7 | 0 | 0 | |||
| CYP2A6 | 0 | 0 | |||
| CYP2A13 | 0 | 0 | |||
| CYP1B1 | 0 | 0 | |||
| CYP1A2 | 0 | 0 | |||
| CYP1A1 | 0 | 0 | |||
| CYP19A1 | 0 | 0 | |||
| CYP17A1 | 0 | 0 | |||
| CYP11B1 | 0 | 0 | |||
| CYLD | 0 | 0 | |||
| CYFIP1 | 0 | 0 | |||
| CYBA | 0 | 0 | |||
| CXCR4 | 胃腺癌,非小细胞肺癌 | 顺铂,多西他赛, | 1 | 2 | |
| CXCL8 | 0 | 0 | |||
| CXCL10 | 0 | 0 | |||
| CX3CL1 | 非小细胞肺癌 | 阿特朱单抗，阿替利珠单抗, | 1 | 1 | |
| CUX1 | 0 | 0 | |||
| CUL4B | 0 | 0 | |||
| CUL4A | 0 | 0 | |||
| CUL3 | 0 | 0 | |||
| CUL1 | 0 | 0 | |||
| CTNND2 | 0 | 0 | |||
| CTNND1 | 0 | 0 | |||
| CTNNB1 | 侵袭性纤维化,结直肠癌,硬纤维瘤病,肝母细胞瘤,黑色素瘤 | Celecoxib,CTLA-4 Antibody,Meloxicam,PD-L1 Antibody, | 7 | 17 | |
| CTNNA2 | 0 | 0 | |||
| CTNNA1 | 0 | 0 | |||
| CTLA4 | 非小细胞肺癌 | 阿特朱单抗，阿替利珠单抗,伊匹单抗, | 2 | 2 | |
| CTIF | 0 | 0 | |||
| CTCF | 0 | 0 | |||
| CTAG2 | 多发性骨髓瘤 | Adoptive T-cell Transfer, | 1 | 1 | |
| CTAG1B | 多发性骨髓瘤 | Adoptive T-cell Transfer, | 1 | 1 | |
| CST7 | 0 | 0 | |||
| CSNK2A1 | 0 | 0 | |||
| CSNK1G3 | 0 | 0 | |||
| CSNK1A1 | 0 | 0 | |||
| CSMD3 | 0 | 0 | |||
| CSMD1 | 0 | 0 | |||
| CSK | 0 | 0 | |||
| CSF3R | 非典型慢性粒细胞白血病,慢性中性粒细胞白血病 | 芦可替尼/鲁索利替尼/鲁索替尼, | 2 | 4 | |
| CSF1R | 急性淋巴细胞白血病 | GW-2580,伊马替尼, | 1 | 1 | |
| CSF1 | 腱膜巨细胞瘤 | 培西达替尼, | 1 | 1 | |
| CSDE1 | 0 | 0 | |||
| CRYBG3 | 0 | 0 | |||
| CRTC1 | 0 | 0 | |||
| CROT | 0 | 0 | |||
| CRNKL1 | 0 | 0 | |||
| CRLF2 | 急性淋巴细胞白血病,成人B淋巴细胞白血病,儿童B细胞急性淋巴细胞白血病,儿童B细胞淋巴细胞白血病,前体B淋巴细胞淋巴瘤/白血病 | JAK Inhibitor I, | 6 | 15 | |
| CRKL | 非小细胞肺癌,胃癌 | 达沙替尼,吉非替尼, | 1 | 2 | |
| CREBBP | 非小细胞肺癌 | C646, | 1 | 1 | |
| CREB3L2 | 0 | 0 | |||
| CREB3L1 | 0 | 0 | |||
| CREB1 | 0 | 0 | |||
| CRBN | 多发性骨髓瘤 | 来那度胺,泊马度胺, | 1 | 1 | |
| CPS1 | 0 | 0 | |||
| CPLANE1 | 0 | 0 | |||
| COX18 | 0 | 0 | |||
| COPS3 | 0 | 0 | |||
| COPS2 | 0 | 0 | |||
| COP1 | 0 | 0 | |||
| COMT | 0 | 0 | |||
| COL5A3 | 0 | 0 | |||
| COL5A2 | 0 | 0 | |||
| COL5A1 | 0 | 0 | |||
| COL2A1 | 0 | 0 | |||
| COL26A1 | 0 | 0 | |||
| COL22A1 | 0 | 0 | |||
| COL1A1 | 0 | 0 | |||
| COL15A1 | 0 | 0 | |||
| COL11A1 | 0 | 0 | |||
| CNTNAP5 | 0 | 0 | |||
| CNTNAP4 | 0 | 0 | |||
| CNTNAP2 | 0 | 0 | |||
| CNTNAP1 | 0 | 0 | |||
| CNTN5 | 0 | 0 | |||
| CNTN1 | 0 | 0 | |||
| CNOT8 | 0 | 0 | |||
| CNOT4 | 0 | 0 | |||
| CNOT3 | 0 | 0 | |||
| CNKSR3 | 0 | 0 | |||
| CLTC | 0 | 0 | |||
| CLSPN | 0 | 0 | |||
| CLP1 | 0 | 0 | |||
| CLMN | 0 | 0 | |||
| CLK2 | 0 | 0 | |||
| CLDN18 | 0 | 0 | |||
| CLCC1 | 0 | 0 | |||
| CKS1B | 0 | 0 | |||
| CIITA | 0 | 0 | |||
| CIC | 结肠癌,肺癌,黑色素瘤,胰腺癌 | 司美替尼,曲美替尼,维莫非尼, | 1 | 9 | |
| CHUK | 0 | 0 | |||
| CHST3 | 0 | 0 | |||
| CHRM2 | 0 | 0 | |||
| CHN1 | 0 | 0 | |||
| CHI3L1 | 0 | 0 | |||
| CHFR | 0 | 0 | |||
| CHEK2 | 乳腺癌,癌症,前列腺癌 | 4 | 5 | ||
| CHEK1 | 小细胞肺癌 | 奥拉帕利,Prexasertib, | 顺铂, | 1 | 1 |
| CHD9 | 0 | 0 | |||
| CHD8 | 0 | 0 | |||
| CHD7 | 0 | 0 | |||
| CHD6 | 0 | 0 | |||
| CHD4 | 0 | 0 | |||
| CHD3 | 0 | 0 | |||
| CHD2 | 0 | 0 | |||
| CHD1L | 0 | 0 | |||
| CHD1 | 0 | 0 | |||
| CFTR | 0 | 0 | |||
| CFLAR | 前列腺癌 | 比卡鲁胺, | 1 | 1 | |
| CFHR2 | 0 | 0 | |||
| CFHR1 | 0 | 0 | |||
| CFH | 0 | 0 | |||
| CETN2 | 0 | 0 | |||
| CEP57 | 0 | 0 | |||
| CEP290 | 0 | 0 | |||
| CEP120 | 0 | 0 | |||
| CENPA | 0 | 0 | |||
| CEBPA | 急性髓性白血病 | All-trans Retinoic Acid,OICR-9429, | 3 | 9 | |
| CDX2 | 结直肠癌 | 1 | 1 | ||
| CDRT4 | 0 | 0 | |||
| CDO1 | 0 | 0 | |||
| CDKNIB | 0 | 0 | |||
| CDKN2C | 0 | 0 | |||
| CDKN2B | 急性早幼粒细胞白血病、尤因肉瘤、肾细胞癌 | Linsitinib,哌柏西利,帕博西尼,帕博西林, | 2 | 3 | |
| CDKN2A | 胆管癌,皮肤纤维肉瘤突起,食管鳞状细胞癌,尤因肉瘤,胃肠道间质瘤,多形胶质母细胞瘤,头颈鳞状细胞癌,HER2受体阴性乳腺癌,非小细胞肺癌,黑色素瘤,口咽癌,卵巢癌,胰腺癌,PED内科低级别胶质瘤（PLGG）,肾细胞癌,肉瘤,皮肤黑色素瘤 | 阿法替尼,西妥昔单抗,EGFR Inhibitor,Flavopiridol,来曲唑片,Linsitinib,哌柏西利,帕博西尼,帕博西林,帕尼单抗, | 9 | 28 | |
| CDKN1C | 0 | 0 | |||
| CDKN1B | 乳腺癌、头颈部鳞状细胞癌 | 拉帕替尼, | 氟尿嘧啶,顺铂, | 2 | 2 |
| CDKN1A | 结直肠癌,视网膜母细胞瘤 | 氟尿嘧啶, | 2 | 2 | |
| CDKL3 | 0 | 0 | |||
| CDK9 | 神经母细胞瘤 | Dinaciclib (SCH727965), | 1 | 1 | |
| CDK8 | 0 | 0 | |||
| CDK7 | 0 | 0 | |||
| CDK6 | 雌激素受体阳性乳腺癌 | 玻玛西林,玻玛西尼,氟维司群,哌柏西利,帕博西尼,帕博西林, | 2 | 3 | |
| CDK5RAP2 | 0 | 0 | |||
| CDK5 | 0 | 0 | |||
| CDK4 | 肺泡横纹肌肉瘤,雌激素受体阳性乳腺癌,脂肪肉瘤,肉瘤,皮肤黑色素瘤 | 阿培利司,哌柏西利,帕博西尼,帕博西林,哌柏西利,帕博西尼,帕博西林,瑞博西尼, | 4 | 6 | |
| CDK2 | 三受体阴性乳腺癌 | 艾日布林, | 卡铂, | 1 | 1 |
| CDK13 | 0 | 0 | |||
| CDK12 | 卵巢浆液性癌 | 奥拉帕利, | 1 | 1 | |
| CDK10 | 0 | 0 | |||
| CDK1 | 0 | 0 | |||
| CDH9 | 0 | 0 | |||
| CDH6 | 0 | 0 | |||
| CDH5 | 0 | 0 | |||
| CDH23 | 0 | 0 | |||
| CDH20 | 0 | 0 | |||
| CDH2 | 0 | 0 | |||
| CDH18 | 0 | 0 | |||
| CDH12 | 0 | 0 | |||
| CDH11 | 0 | 0 | |||
| CDH10 | 0 | 0 | |||
| CDH1 | 胃癌 | 1 | 1 | ||
| CDC73 | 0 | 0 | |||
| CDC42 | 0 | 0 | |||
| CDC27 | 0 | 0 | |||
| CDC25C | 0 | 0 | |||
| CDC25B | 0 | 0 | |||
| CDA | 0 | 0 | |||
| CD79B | 0 | 0 | |||
| CD79A | 0 | 0 | |||
| CD74 | 0 | 0 | |||
| CD70 | 0 | 0 | |||
| CD5L | 0 | 0 | |||
| CD52 | 0 | 0 | |||
| CD44 | 癌症 | RG7356, | 1 | 1 | |
| CD40 | 0 | 0 | |||
| CD33 | 0 | 0 | |||
| CD276 | 0 | 0 | |||
| CD274 | 乳腺癌,癌症,头颈部鳞状细胞癌,非小细胞肺癌,肺鳞状细胞癌,黑色素瘤,默克尔细胞癌,卵巢浆液性癌,乳头状甲状腺癌,胃癌 | 阿特朱单抗，阿替利珠单抗,阿维单抗 巴文西亚,度伐利尤单抗，德瓦鲁单抗,伊匹单抗,纳武单抗（纳武利尤单抗）,派姆单抗（帕博利珠单抗）,Radiation, | 1 | 21 | |
| CD22 | 0 | 0 | |||
| CD19 | 0 | 0 | |||
| CCT6B | 0 | 0 | |||
| CCT5 | 0 | 0 | |||
| CCT3 | 0 | 0 | |||
| CCR4 | 0 | 0 | |||
| CCNE1 | 乳腺癌,雌激素受体阳性乳腺癌,胃腺鳞癌,卵巢癌,卵巢浆液性囊腺癌 | BMS-387032 (SNS-032),MK-7965,氟维司群,MK-2206,哌柏西利,帕博西尼,帕博西林, | 3 | 8 | |
| CCND3 | T细胞白血病 | 哌柏西利,帕博西尼,帕博西林, | 1 | 1 | |
| CCND2 | 胃癌 | 2 | 5 | ||
| CCND1 | 乳腺癌,雌激素受体阳性乳腺癌,头颈部鳞状细胞癌,非小细胞肺癌,套细胞淋巴瘤,卵巢癌,肾细胞癌,皮肤黑色素瘤 | 哌柏西利,帕博西尼,帕博西林,索拉非尼, | 卡铂,紫杉醇,他莫昔芬, | 3 | 15 |
| CCNB3 | 0 | 0 | |||
| CCNA2 | 0 | 0 | |||
| CCNA1 | 0 | 0 | |||
| CCDC6 | 0 | 0 | |||
| CCDC168 | 0 | 0 | |||
| CBX4 | 0 | 0 | |||
| CBR4 | 0 | 0 | |||
| CBR3 | 0 | 0 | |||
| CBR1 | 0 | 0 | |||
| CBLC | 癌症 | 奥拉帕利, | 1 | 1 | |
| CBLB | 非小细胞肺癌 | 1 | 1 | ||
| CBL | 少年骨髓单核细胞白血病,非小细胞肺癌 | SU11274, | 6 | 7 | |
| CBFB | 急性髓性白血病 | 1 | 1 | ||
| CBFA2T3 | 急性髓性白血病 | 1 | 1 | ||
| CBARP | 0 | 0 | |||
| CAST | 0 | 0 | |||
| CASR | 0 | 0 | |||
| CASQ2 | 0 | 0 | |||
| CASP9 | 0 | 0 | |||
| CASP8 | 骨尤因肉瘤,神经母细胞瘤 | 西他土珠, | 2 | 2 | |
| CASP7 | 0 | 0 | |||
| CASP1 | 0 | 0 | |||
| CARM1 | 0 | 0 | |||
| CARD11 | 0 | 0 | |||
| CAPN7 | 0 | 0 | |||
| CAMTA1 | 0 | 0 | |||
| CAMKK2 | 0 | 0 | |||
| CAMK2G | 0 | 0 | |||
| CALR | 慢性骨髓增生性疾病,原发性血小板增多症,骨髓纤维化 | Pegylated IFN-alpha-2a, | 2 | 8 | |
| CALM2 | 0 | 0 | |||
| CALD1 | 0 | 0 | |||
| CADM2 | 0 | 0 | |||
| CACNA1E | 0 | 0 | |||
| CACNA1D | 0 | 0 | |||
| CAB39 | 0 | 0 | |||
| CA10 | 0 | 0 | |||
| C9orf72 | 0 | 0 | |||
| C8orf34 | 0 | 0 | |||
| C6orf118 | 0 | 0 | |||
| C5orf15 | 0 | 0 | |||
| C3orf70 | 0 | 0 | |||
| C2CD6 | 0 | 0 | |||
| C22orf23 | 0 | 0 | |||
| C20orf96 | 0 | 0 | |||
| C1S | 0 | 0 | |||
| C1R | 0 | 0 | |||
| C1QA | 0 | 0 | |||
| C19MC | 0 | 0 | |||
| C14orf177 | 0 | 0 | |||
| BUB3 | 0 | 0 | |||
| BUB1B | 0 | 0 | |||
| BUB1 | 0 | 0 | |||
| BTLA | 0 | 0 | |||
| BTK | 慢性淋巴细胞白血病 | 伊布替尼, | 3 | 4 | |
| BTG2 | 0 | 0 | |||
| BTG1 | 0 | 0 | |||
| BTF3 | 0 | 0 | |||
| BRWD1 | 0 | 0 | |||
| BRSK1 | 0 | 0 | |||
| BRS3 | 0 | 0 | |||
| BRMS1L | 0 | 0 | |||
| BRIP1 | 0 | 0 | |||
| BRINP3 | 0 | 0 | |||
| BRF1 | 0 | 0 | |||
| BRD7 | 0 | 0 | |||
| BRD4 | 透明细胞肾细胞癌,坚果中线癌 | 比拉瑞塞,JQ1, | 2 | 4 | |
| BRD3 | 0 | 0 | |||
| BRD2 | 0 | 0 | |||
| BRCC3 | 0 | 0 | |||
| BRCA2 | 乳腺癌,癌症,上皮性卵巢癌,HER2受体阴性乳腺癌,卵巢癌,卵巢浆液性癌,胰腺癌,前列腺癌,三受体阴性乳腺癌 | 西地尼布,CX-3543,CX-5461,Iniparib,丝裂霉素C,奥拉帕利,PLATINUM,卢卡帕尼,他拉唑帕尼,维利帕尼, | 卡铂,顺铂,吉西他滨, | 12 | 36 |
| BRCA1 | 乳腺癌,癌症,上皮性卵巢癌,Her2受体阴性乳腺癌,恶性间皮瘤,卵巢癌,卵巢浆膜癌,胰腺癌,前列腺癌,三受体阴性乳腺癌 | 西地尼布,CX-3543,CX-5461,奥拉帕利,PLATINUM,卢卡帕尼,他拉唑帕尼,Taxane,维利帕尼, | 卡铂,顺铂,吉西他滨,长春瑞滨, | 20 | 46 |
| BRAF | 未分化甲状腺癌,乳腺癌,癌症,胆管癌,透明细胞肉瘤,结肠癌,结直肠癌,神经节胶质瘤,胃肠神经内分泌肿瘤,胃肠道间质瘤,多形胶质母细胞瘤,毛细胞白血病,组织细胞瘤,朗格汉斯细胞组织细胞病,LAR咽鳞状细胞癌,肺腺癌,非小细胞肺癌,恶性结膜黑色素瘤,恶性胶质瘤,恶性周围神经鞘肿瘤,黑色素瘤,多发性骨髓瘤,骨髓瘤,卵巢癌,卵巢囊腺癌,卵巢浆液性癌,胰腺癌,乳头状甲状腺癌,PEDI心房低级别胶质瘤（PLGG）,毛细胞星形细胞瘤,多形性黄原性星形细胞瘤,肉瘤,皮肤黑色素瘤,梭形细胞肉瘤,甲状腺癌 | 阿培利司,Refametinib,贝伐单抗,Dactolisib,比美替尼、贝美替尼,BMS-754807,卡培他滨,西妥昔单抗,CI-1040,考比替尼,达拉非尼,达沙替尼,康奈非尼,厄洛替尼,依维莫司,Fluorouracil,GDC-0879,Pictilisib,吉非替尼,GSK 1120212,LY3009120,MEK Inhibitor,Nutlin-3,帕尼单抗,PD0325901,PD 0325901,帕妥珠单抗,Pictilisib,PLX4720,RDEA119,瑞戈非尼,RO4987655,司美替尼,索拉非尼,TAK-733,西罗莫司,曲美替尼,U0126,维莫非尼, | 伊立替康,奥沙利铂, | 59 | 303 |
| BPTF | 0 | 0 | |||
| BORCS8-MEF2B | 0 | 0 | |||
| BNC2 | 0 | 0 | |||
| BMX | 0 | 0 | |||
| BMPR2 | 0 | 0 | |||
| BMPR1A | 0 | 0 | |||
| BLM | 0 | 0 | |||
| BLK | 0 | 0 | |||
| BLCAP | 0 | 0 | |||
| BIRC7 | 结肠癌 | 顺铂, | 1 | 1 | |
| BIRC5 | Her2受体阳性乳腺癌,非小细胞肺癌 | PLATINUM,Taxane,曲妥珠单抗, | 2 | 2 | |
| BIRC3 | 慢性淋巴细胞白血病 | 1 | 1 | ||
| BIRC2 | 0 | 0 | |||
| BICC1 | 0 | 0 | |||
| BCR | 0 | 0 | |||
| BCORL1 | 0 | 0 | |||
| BCOR | 胃癌 | 1 | 1 | ||
| BCLAF1 | 0 | 0 | |||
| BCL9 | 0 | 0 | |||
| BCL6 | 0 | 0 | |||
| BCL3 | 0 | 0 | |||
| BCL2L2 | 0 | 0 | |||
| BCL2L14 | 0 | 0 | |||
| BCL2L11 | 慢性髓系白血病,非小细胞肺癌 | EGFR Inhibitor,伊马替尼, | 1 | 2 | |
| BCL2L1 | 0 | 0 | |||
| BCL2A1 | 0 | 0 | |||
| BCL2 | 弥漫性大B细胞淋巴瘤 | 3 | 4 | ||
| BCL11B | 0 | 0 | |||
| BCL11A | 0 | 0 | |||
| BCL10 | 0 | 0 | |||
| BCAS3 | 0 | 0 | |||
| BCAS1 | 0 | 0 | |||
| BBS9 | 0 | 0 | |||
| BBC3 | 0 | 0 | |||
| BAZ2B | 0 | 0 | |||
| BAX | 0 | 0 | |||
| BARD1 | 结直肠癌 | 奥拉帕利, | 1 | 1 | |
| BAP1 | 透明细胞肾细胞癌,恶性间皮瘤,肾癌,肾细胞癌,葡萄膜黑色素瘤 | 依维莫司,Apitolisib,LBH-589,MC1568,Mocetinostat,奥拉帕利,舒尼替尼,曲古抑菌素 A,伏立诺他, | 丙戊酸钠, | 4 | 9 |
| BAK1 | 0 | 0 | |||
| BAD | 0 | 0 | |||
| BACH1 | 0 | 0 | |||
| BABAM2 | 0 | 0 | |||
| BABAM1 | 0 | 0 | |||
| B4GALT3 | 0 | 0 | |||
| B4GALT1 | 肾细胞癌 | 1 | 1 | ||
| B2M | 结直肠癌,皮肤黑色素瘤 | 纳武单抗（纳武利尤单抗）,派姆单抗（帕博利珠单抗）, | 2 | 2 | |
| AXL | 食管鳞状细胞癌 | 1 | 1 | ||
| AXIN2 | 0 | 0 | |||
| AXIN1 | 0 | 0 | |||
| AURKB | 0 | 0 | |||
| AURKA | 宫颈腺癌,食管腺癌,食管鳞状细胞癌,雌激素受体阳性乳腺癌,非小细胞肺癌,卵巢癌,卵巢浆液性癌 | Alisertib,PLATINUM, | 氟尿嘧啶,顺铂,紫杉醇,他莫昔芬, | 3 | 7 |
| ATXN1L | 黑素瘤,胰腺癌 | 达拉非尼,曲美替尼,维莫非尼, | 1 | 2 | |
| ATRX | 星形细胞瘤,多形性胶质母细胞瘤,骨肉瘤,小儿低级别胶质瘤（PLGG） | AZ20,替莫唑胺,VE-821, | 洛莫司汀,丙卡巴肼,长春新碱, | 2 | 4 |
| ATRIP | 0 | 0 | |||
| ATR | 子宫内膜癌 | 1 | 1 | ||
| ATP9B | 0 | 0 | |||
| ATP7A | 0 | 0 | |||
| ATP2B3 | 0 | 0 | |||
| ATP1B2 | 0 | 0 | |||
| ATP1A1 | 0 | 0 | |||
| ATP12A | 0 | 0 | |||
| ATP11B | 0 | 0 | |||
| ATM | 癌症,慢性淋巴细胞白血病,胃腺癌,多形性胶质母细胞瘤,血液癌,肺腺癌,肺癌,套细胞淋巴瘤,黑色素瘤,胰腺癌,前列腺癌,胃癌 | KU-0060648,NU7441,奥拉帕利,司美替尼,替莫唑胺,曲美替尼, | 多柔比星, | 31 | 41 |
| ATIC | 0 | 0 | |||
| ATF1 | 0 | 0 | |||
| ASXL3 | 0 | 0 | |||
| ASXL2 | 0 | 0 | |||
| ASXL1 | 急性髓性白血病,骨髓增生异常综合征,骨髓纤维化 | 2 | 8 | ||
| ASTN2 | 0 | 0 | |||
| ASTN1 | 0 | 0 | |||
| ASS1 | 卵巢癌,肉瘤 | 精氨酸脱亚胺酶,PLATINUM, | 氯喹, | 1 | 2 |
| ASPSCR1 | 0 | 0 | |||
| ASPM | 0 | 0 | |||
| ASNS | 卵巢癌,T细胞白血病 | L-门冬酰胺酶, | 2 | 2 | |
| ASMTL | 0 | 0 | |||
| ASH1L | 0 | 0 | |||
| ASCL4 | 0 | 0 | |||
| ASCL2 | 0 | 0 | |||
| ASCL1 | 非典型畸胎样横纹肌样肿瘤 | 1 | 1 | ||
| ASB18 | 0 | 0 | |||
| ARPC2 | 0 | 0 | |||
| ARNT | 0 | 0 | |||
| ARMC5 | 0 | 0 | |||
| ARL6IP6 | 0 | 0 |
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