菜单 基因医生

该基因是转录因子的基本螺旋环螺旋(bhlh)家族的成员。它通过与e盒(5'-canntg-3')结合激活转录。与其他bhlh蛋白的二聚作用是有效的dna结合所必需的。参与外周神经系统和中枢神经系统中神经元前体的测定。[由RefSeq提供,2008年7月]
This gene is a member of the basic helix-loop-helix (BHLH) family of transcription factors. It activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. Involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system. [provided by RefSeq, Jul 2008]

基因名:ASCL2
别名:ASH2,HASH2,MASH2,bHLHa45
基因ID:430
Chromosome:
(GRCh37)
11 Start: 2289728 End: 2292182 Strand: 
信号通路:  
ASCL2 基因突变与药物