菜单 基因医生

这个基因编码一个分子伴侣,它是包含tcp1复合物(cct)的伴侣蛋白的一个成员,也被称为tcp1环复合物(tric)。这个复合物由两个相同的堆叠环组成,每个环包含八种不同的蛋白质。未折叠的多肽进入复合物的中心腔,并以ATP依赖的方式折叠该复合物可折叠多种蛋白质,包括肌动蛋白和微管蛋白选择性剪接导致多个转录变体[由RefSeq提供,2015年2月]
This gene encodes a molecular chaperone that is a member of the chaperonin-containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]

基因名:CCT6B
别名:Cctz2,CCTZ-2,TSA303,CCT-zeta-2,TCP-1-zeta-2
基因ID:10693
Chromosome:
(GRCh37)
17 Start: 33254878 End: 33307968 Strand: 
信号通路:  
CCT6B 基因突变与药物