菜单 基因医生

这个基因编码丝氨酸/苏氨酸激酶的极光激酶亚家族的一个成员。编码这个亚科另外两个成员的基因位于19号和20号染色体上。这些激酶通过与微管的结合参与有丝分裂和减数分裂过程中染色体排列和分离的调节。这个基因的一个假基因位于8号染色体上。另外,已经发现该基因的剪接转录变体。[由RefSeq提供,2015年9月]
This gene encodes a member of the aurora kinase subfamily of serine/threonine kinases. The genes encoding the other two members of this subfamily are located on chromosomes 19 and 20. These kinases participate in the regulation of alignment and segregation of chromosomes during mitosis and meiosis through association with microtubules. A pseudogene of this gene is located on chromosome 8. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015]

基因名:AURKB
别名:AIK2,AIM1,ARK2,AurB,IPL1,STK5,AIM-1,ARK-2,STK-1,STK12,PPP1R48,aurkb-sv1,aurkb-sv2
基因ID:9212
Chromosome:
(GRCh37)
17 Start: 8108049 End: 8113944 Strand: 
信号通路: 细胞周期 
AURKB 基因突变与药物