菜单 基因医生

该基因编码src原癌基因家族的一个非受体酪氨酸激酶,典型地参与细胞增殖和分化该蛋白在b细胞受体信号传导和b细胞发育中起作用。该蛋白还刺激胰岛素的合成和分泌,对葡萄糖作出反应,并增强一些胰腺β细胞转录因子的表达[由RefSeq提供,2010年8月]
This gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors. [provided by RefSeq, Aug 2010]

基因名:BLK
别名:MODY11
基因ID:640
Chromosome:
(GRCh37)
8 Start: 11351521 End: 11422108 Strand: 
信号通路:  
BLK 基因突变与药物