| 基因名 | 疾病 | 靶向药 | 化疗药 | 基因突变 | 临床解释 |
|---|---|---|---|---|---|
| IFNAR1 | 0 | 0 | |||
| IFITM3 | 0 | 0 | |||
| IFITM1 | 0 | 0 | |||
| IDO2 | 0 | 0 | |||
| IDO1 | 0 | 0 | |||
| IDH2 | 急性髓性白血病,星形细胞瘤,脑胶质瘤,多形性胶质母细胞瘤,骨髓增生异常综合征,外周T细胞淋巴瘤 | 恩西地平, | 4 | 18 | |
| IDH1 | 急性髓性白血病,间变性少突胶质瘤,星形细胞瘤,脑胶质瘤,神经节胶质瘤,多形胶质母细胞瘤,肝内胆管癌,恶性胶质瘤,骨髓增生异常综合征,胰腺导管腺癌。 | AG-120,AGI-5198,BAY 1436032,贝伐单抗,Bis-2-[5-(phenylacetamide)-1,帕纳替尼/普纳替尼/波纳替尼,4-thiadiazol-2-yl]ethyl Sulfide,Bis-2-(5-phenylacetamido-1,舒尼替尼,4-thiadiazol-2-yl)ethyl Sulfide,西妥昔单抗,达沙替尼,GSK321,Tibsovo,奥拉帕利,替莫唑胺, | 7 | 40 | |
| ID3 | 0 | 0 | |||
| ID2 | 0 | 0 | |||
| ICOSLG | 0 | 0 | |||
| Ick | 0 | 0 | |||
| Iars | 0 | 0 | |||
| HYOU1 | 0 | 0 | |||
| HUWE1 | 0 | 0 | |||
| HTR1A | 0 | 0 | |||
| HSPH1 | 结直肠癌,胃腺癌 | 氟尿嘧啶,顺铂,奥沙利铂, | 2 | 3 | |
| HSPD1 | 0 | 0 | |||
| HSPB1 | 胰腺导管腺癌 | 吉西他滨, | 1 | 1 | |
| HSPA8 | 0 | 0 | |||
| HSPA5 | 结直肠癌 | 氟尿嘧啶, | 1 | 1 | |
| HSPA4 | 0 | 0 | |||
| HSPA1B | 0 | 0 | |||
| HSP90AB1 | 0 | 0 | |||
| HSP90AA1 | 0 | 0 | |||
| HSD3B2 | 0 | 0 | |||
| HSD3B1 | 0 | 0 | |||
| HSD17B4 | 0 | 0 | |||
| HSD17B3 | 0 | 0 | |||
| HRH2 | 0 | 0 | |||
| HRAS | 癌症,结直肠癌,滤泡性甲状腺癌,头颈癌,非小细胞肺癌,皮肤鳞状细胞癌,甲状腺癌 | AZD8055,比美替尼、贝美替尼,西妥昔单抗,EGFR Inhibitor,厄洛替尼,依维莫司,PD0325901,司美替尼,维莫非尼, | 10 | 15 | |
| HOXD13 | 0 | 0 | |||
| HOXD11 | 0 | 0 | |||
| HOXC13 | 0 | 0 | |||
| HOXB13 | 前列腺癌 | 1 | 2 | ||
| HOXA9 | 0 | 0 | |||
| HOXA3 | 0 | 0 | |||
| HOXA13 | 0 | 0 | |||
| HOXA11 | 0 | 0 | |||
| HNRNPH1 | 0 | 0 | |||
| HNF4A | 0 | 0 | |||
| HNF1B | 0 | 0 | |||
| HNF1A | 0 | 0 | |||
| HMOX1 | 肾细胞癌 | 索拉非尼,舒尼替尼, | 1 | 1 | |
| HMCN1 | 0 | 0 | |||
| HMBS | 0 | 0 | |||
| HLF | 0 | 0 | |||
| HLA-DRB1 | 0 | 0 | |||
| HLA-DRA | 皮肤黑色素瘤 | 阿特朱单抗，阿替利珠单抗,纳武单抗（纳武利尤单抗）,派姆单抗（帕博利珠单抗）, | 1 | 1 | |
| HLA-C | 结直肠癌 | Adoptive T-cell Transfer, | 1 | 1 | |
| HLA-B | 0 | 0 | |||
| HLA-A | 0 | 0 | |||
| HIST3H3 | 0 | 0 | |||
| HIST2H3D | 0 | 0 | |||
| HIST2H3C | 0 | 0 | |||
| HIST1H4I | 0 | 0 | |||
| HIST1H3J | 0 | 0 | |||
| HIST1H3I | 0 | 0 | |||
| HIST1H3H | 0 | 0 | |||
| HIST1H3G | 0 | 0 | |||
| HIST1H3F | 0 | 0 | |||
| HIST1H3E | 0 | 0 | |||
| HIST1H3D | 0 | 0 | |||
| HIST1H3C | 0 | 0 | |||
| HIST1H3B | 0 | 0 | |||
| HIST1H3A | 0 | 0 | |||
| Hist1h2bo | 0 | 0 | |||
| HIST1H2BD | 0 | 0 | |||
| Hist1h2bc | 0 | 0 | |||
| Hist1h2al | 0 | 0 | |||
| Hist1h2ac | 0 | 0 | |||
| HIST1H1E | 0 | 0 | |||
| HIST1H1D | 0 | 0 | |||
| HIST1H1C | 0 | 0 | |||
| HIP1 | 0 | 0 | |||
| HIF1A | 结直肠癌,胰腺腺癌,肾细胞癌,肉瘤 | 帕唑帕尼,培唑帕尼, | 3 | 4 | |
| HGF | 多形胶质母细胞瘤 | SGX523, | 1 | 1 | |
| HFE | 0 | 0 | |||
| HEY1 | 0 | 0 | |||
| HES1 | 0 | 0 | |||
| HERC2 | 0 | 0 | |||
| HECW1 | 0 | 0 | |||
| HDAC9 | 0 | 0 | |||
| HDAC8 | 0 | 0 | |||
| HDAC7 | 0 | 0 | |||
| HDAC6 | 0 | 0 | |||
| HDAC4 | 0 | 0 | |||
| HDAC3 | 0 | 0 | |||
| HDAC2 | 肾细胞癌 | 艾贝司他,帕唑帕尼,培唑帕尼, | 1 | 1 | |
| HDAC1 | 0 | 0 | |||
| HCN1 | 0 | 0 | |||
| HCLS1 | 0 | 0 | |||
| HCK | 0 | 0 | |||
| HCAR2 | 0 | 0 | |||
| HAVCR2 | 非小细胞肺癌 | PD-1 Inhibitor,TIM-3 Inhibitor, | 1 | 2 | |
| HAUS6 | 0 | 0 | |||
| HAUS2 | 0 | 0 | |||
| HAPLN1 | 0 | 0 | |||
| H3f3c | 0 | 0 | |||
| H3F3B | 软骨母细胞瘤 | 1 | 1 | ||
| H3F3A | 骨巨细胞瘤,弥漫性固有桥脑胶质瘤,多形性胶质母细胞瘤,小儿低级别胶质瘤（PLGG）。 | 3 | 5 | ||
| H3C8 | 0 | 0 | |||
| H3C7 | 0 | 0 | |||
| H3C6 | 0 | 0 | |||
| H3C4 | 0 | 0 | |||
| H3C3 | 0 | 0 | |||
| H3C2 | 0 | 0 | |||
| H3C14 | 0 | 0 | |||
| H3C13 | 0 | 0 | |||
| H3C11 | 0 | 0 | |||
| H3C10 | 0 | 0 | |||
| H3C1 | 0 | 0 | |||
| H3-4 | 0 | 0 | |||
| H3-3B | 0 | 0 | |||
| H3-3A | 0 | 0 | |||
| H2BC5 | 0 | 0 | |||
| H2AX | 0 | 0 | |||
| H1-2 | 0 | 0 | |||
| GUSB | 0 | 0 | |||
| GSTT1 | 0 | 0 | |||
| GSTP1 | 结直肠癌,卵巢癌 | FolfoxProtocol, | 卡铂,顺铂,紫杉醇, | 2 | 2 |
| GSTM5 | 0 | 0 | |||
| GSTM4 | 0 | 0 | |||
| GSTM3 | 0 | 0 | |||
| GSTM1 | 0 | 0 | |||
| GSTA1 | 0 | 0 | |||
| GSK3B | 0 | 0 | |||
| GRM8 | 0 | 0 | |||
| GRM3 | 0 | 0 | |||
| GRIN2A | 0 | 0 | |||
| GRIK3 | 0 | 0 | |||
| GRID1 | 0 | 0 | |||
| GREM1 | 0 | 0 | |||
| GRB7 | 0 | 0 | |||
| GRB2 | 0 | 0 | |||
| GPX1 | 0 | 0 | |||
| GPS2 | 0 | 0 | |||
| GPR158 | 0 | 0 | |||
| GPR124 | 0 | 0 | |||
| GPR101 | 0 | 0 | |||
| GPM6A | 0 | 0 | |||
| GPC3 | 0 | 0 | |||
| GPAT3 | 0 | 0 | |||
| GOPC | 0 | 0 | |||
| GNRHR | 0 | 0 | |||
| GNG2 | 0 | 0 | |||
| GNAS | 膀胱尿路上皮癌,乳腺癌,慢性淋巴细胞白血病,透明细胞肾细胞癌,结直肠癌,食管癌,滤泡性甲状腺癌,肝内胆管癌,非小细胞肺癌,黑色素瘤,腹膜假黏液瘤 | 西妥昔单抗,厄洛替尼,吉非替尼,Radioactive Iodine,维莫非尼, | 氟尿嘧啶,顺铂,伊立替康, | 4 | 12 |
| GNAQ | 皮肤黑色素瘤,葡萄膜黑色素瘤 | AEB071,Refametinib,卡博替尼,JQ1,PD0325901,PLX4720,司美替尼,曲美替尼,维莫非尼, | 3 | 8 | |
| GNA13 | 0 | 0 | |||
| GNA12 | 0 | 0 | |||
| GNA11 | 葡萄膜黑色素瘤 | AEB071,卡博替尼,JQ1,PD0325901,司美替尼,曲美替尼, | 2 | 5 | |
| GMPS | 0 | 0 | |||
| GMEB1 | 0 | 0 | |||
| GLI3 | 0 | 0 | |||
| GLI2 | 0 | 0 | |||
| GLI1 | 细胞周瘤 | 1 | 1 | ||
| GLB1L3 | 0 | 0 | |||
| GKN2 | 0 | 0 | |||
| GJB2 | 0 | 0 | |||
| GIGYF1 | 0 | 0 | |||
| GID4 | 0 | 0 | |||
| GGH | 0 | 0 | |||
| GFRAL | 0 | 0 | |||
| GEN1 | 0 | 0 | |||
| GDF15 | 0 | 0 | |||
| GDF1 | 0 | 0 | |||
| GATA6 | 0 | 0 | |||
| GATA4 | 0 | 0 | |||
| GATA3 | 0 | 0 | |||
| GATA2 | 肺腺癌 | 硼替佐米, | 法舒地尔, | 1 | 1 |
| GATA1 | 0 | 0 | |||
| GAST | 0 | 0 | |||
| GAS6 | 口腔鳞状细胞癌 | 多西他赛, | 1 | 2 | |
| GAPDH | 0 | 0 | |||
| GANC | 0 | 0 | |||
| GALNT14 | 0 | 0 | |||
| GALNT12 | 0 | 0 | |||
| GALNT11 | 0 | 0 | |||
| GADD45A | 卵巢癌 | 1 | 1 | ||
| GABRP | 0 | 0 | |||
| GABRA6 | 0 | 0 | |||
| GABRA2 | 0 | 0 | |||
| GAB2 | 0 | 0 | |||
| G6PC3 | 0 | 0 | |||
| G6PC | 0 | 0 | |||
| G3BP2 | 0 | 0 | |||
| G3BP1 | 0 | 0 | |||
| FZR1 | 0 | 0 | |||
| FZD10 | 0 | 0 | |||
| FZD1 | 0 | 0 | |||
| FYN | 0 | 0 | |||
| FXR1 | 0 | 0 | |||
| FUS | 0 | 0 | |||
| FUBP1 | 0 | 0 | |||
| FSCB | 0 | 0 | |||
| FRYL | 0 | 0 | |||
| FRS2 | 0 | 0 | |||
| FRMPD4 | 0 | 0 | |||
| FRK | 0 | 0 | |||
| FRG1 | 0 | 0 | |||
| FRAS1 | 0 | 0 | |||
| FPGS | 0 | 0 | |||
| FOXQ1 | 0 | 0 | |||
| FOXP3 | 乳腺癌 | 表柔比星, | 1 | 1 | |
| FOXP1 | 弥漫性大B细胞淋巴瘤 | 1 | 1 | ||
| FOXO4 | 0 | 0 | |||
| FOXO3 | 脉络丛癌 | 1 | 2 | ||
| FOXO1 | 肺泡横纹肌肉瘤 | Bromodomain Inhibitor, | 2 | 3 | |
| FOXL2 | 卵巢颗粒细胞瘤 | 1 | 2 | ||
| FOXA2 | 0 | 0 | |||
| FOXA1 | 0 | 0 | |||
| FOS | 骨上皮样血管瘤 | 厄贝沙坦, | 2 | 2 | |
| FOLR3 | 0 | 0 | |||
| FOLH1 | 0 | 0 | |||
| FNTB | 卵巢癌 | 洛那法尼, | 1 | 1 | |
| FNTA | 0 | 0 | |||
| FNDC4 | 0 | 0 | |||
| FN1 | 0 | 0 | |||
| FMR1 | 0 | 0 | |||
| FMO1 | 0 | 0 | |||
| FMN2 | 0 | 0 | |||
| FLT4 | 血管肉瘤 | 帕唑帕尼,培唑帕尼, | 1 | 1 | |
| FLT3 | 急性髓细胞白血病,急性早幼粒细胞白血病,成人B淋巴细胞白血病,结直肠癌,肾细胞癌 | Tyrphostin,All-trans Retinoic Acid,AS602868,Gilteritinib,JQ1,Lestaurtinib (CEP-701),米哚妥林,坦度替尼,尼洛替尼,哌柏西利,帕博西尼,帕博西林,帕纳替尼/普纳替尼/波纳替尼,奎扎替尼,Quizartinib (AC220),瑞戈非尼,司美替尼,索拉非尼,舒尼替尼,SU5614,舒尼替尼, | 蒽环类,阿糖胞苷,柔红霉素, | 15 | 82 |
| FLT1 | 0 | 0 | |||
| FLOT1 | 0 | 0 | |||
| FLNC | 0 | 0 | |||
| FLNA | 0 | 0 | |||
| FLI1 | 尤因肉瘤 | 2 | 2 | ||
| FLG | 0 | 0 | |||
| FLCN | 乳头状肾细胞癌 | 依维莫司,Sirolimus [USAN:BAN:INN], | 2 | 2 | |
| FKBP5 | 0 | 0 | |||
| FIP1L1 | 0 | 0 | |||
| FHIT | 0 | 0 | |||
| FH | 0 | 0 | |||
| FGR | 0 | 0 | |||
| FGFR4 | 肺泡横纹肌肉瘤,Her2受体阳性乳腺癌 | 多韦替尼,FGF/VEGF Receptor Tyrosine Kinase Inhibitor,PD173074,帕纳替尼/普纳替尼/波纳替尼, | 1 | 2 | |
| FGFR3 | 肾上腺癌,膀胱癌,癌症,肺腺癌,骨髓瘤,皮肤黑色素瘤,thanatophoric发育不良,最常见的形式是散发性,致死性侏儒症,尿路上皮癌 | AZ12908010,AZD4547,Infigratinib,Infigratinib,多韦替尼,厄达替尼,厄达替尼,帕唑帕尼,培唑帕尼,PD173074,SU5402,维莫非尼, | 20 | 29 | |
| FGFR2 | 乳腺癌,癌,胆管癌,子宫内膜癌,肝细胞癌,肺腺癌,卵巢透明细胞癌,乳头状肾细胞癌,直肠癌,胃癌,尿路上皮癌 | 46834118,AZD4547,Infigratinib,Infigratinib,Derazantinib,多韦替尼,厄达替尼,氟维司群,厄达替尼,帕唑帕尼,培唑帕尼,PD173074,帕纳替尼/普纳替尼/波纳替尼,Futibatinib, | 12 | 29 | |
| FGFR1 | 膀胱癌,骨尤因肉瘤,乳腺癌,癌症,慢性骨髓单核细胞白血病,慢性骨髓增生性疾病,结直肠癌,雌激素受体阳性乳腺癌,胃腺癌,头颈部鳞状细胞癌,血液癌,肺癌,非小细胞肺癌,肺鳞状细胞癌细胞癌,小儿低级别胶质瘤（PLGG）,毛细胞性星形细胞瘤,肉瘤 | AZD4547,Infigratinib,Infigratinib,多韦替尼,Dovitinib Dilactic Acid (TKI258 Dilactic Acid),FGF/VEGF Receptor Tyrosine Kinase Inhibitor,PD173074,米哚妥林,帕唑帕尼,培唑帕尼,帕纳替尼/普纳替尼/波纳替尼, | 4-羟基他莫昔芬, | 7 | 32 |
| FGF7 | 0 | 0 | |||
| FGF6 | 0 | 0 | |||
| FGF4 | 0 | 0 | |||
| FGF3 | 乳腺癌,肝细胞癌 | 多韦替尼,索拉非尼, | 1 | 2 | |
| FGF23 | 0 | 0 | |||
| FGF2 | 急性髓性白血病 | Quizartinib (AC220), | 1 | 1 | |
| FGF19 | 0 | 0 | |||
| FGF16 | 0 | 0 | |||
| FGF14 | 0 | 0 | |||
| FGF13 | 前列腺癌 | 1 | 1 | ||
| FGF12 | 0 | 0 | |||
| FGF10 | 0 | 0 | |||
| FGD4 | 0 | 0 | |||
| FGD1 | 0 | 0 | |||
| FGA | 0 | 0 | |||
| FES | 0 | 0 | |||
| FCRL4 | 0 | 0 | |||
| FCGR3B | 0 | 0 | |||
| FCGR3A | 乳腺癌 | 曲妥珠单抗, | 1 | 2 | |
| FCGR2C | 0 | 0 | |||
| FCGR2B | 乳腺癌 | 1 | 1 | ||
| FCGR2A | 乳腺癌 | 1 | 2 | ||
| FCGR1A | 0 | 0 | |||
| FBXW7 | 癌症,结直肠癌,肾细胞癌,T细胞急性淋巴细胞白血病 | 西妥昔单抗,依维莫司,MTOR Inhibitors,帕尼单抗,西罗莫司,瑞戈非尼, | 9 | 12 | |
| FBXO11 | 0 | 0 | |||
| FBXL7 | 0 | 0 | |||
| FBN2 | 0 | 0 | |||
| FAT4 | 0 | 0 | |||
| FAT3 | 0 | 0 | |||
| FAT2 | 0 | 0 | |||
| FAT1 | 0 | 0 | |||
| FASLG | 0 | 0 | |||
| FAS | 0 | 0 | |||
| FAP | 0 | 0 | |||
| FANCM | 0 | 0 | |||
| FANCL | 0 | 0 | |||
| FANCI | 0 | 0 | |||
| FANCG | 0 | 0 | |||
| FANCF | 0 | 0 | |||
| FANCE | 0 | 0 | |||
| FANCD2 | 0 | 0 | |||
| FANCC | 胰腺癌 | 马法兰，米尔法兰,丝裂霉素C, | 苯丁酸氮芥,顺铂,吉西他滨, | 1 | 1 |
| FANCB | 0 | 0 | |||
| FANCA | 前列腺癌 | 顺铂, | 1 | 1 | |
| FAN1 | 0 | 0 | |||
| FAM46C | 0 | 0 | |||
| FAM175A | 0 | 0 | |||
| FAM157B | 0 | 0 | |||
| FAM155A | 0 | 0 | |||
| FAM153B | 0 | 0 | |||
| FAM149A | 0 | 0 | |||
| FAM135B | 0 | 0 | |||
| FAM131B | 0 | 0 | |||
| FAF1 | 0 | 0 | |||
| F8 | 0 | 0 | |||
| F3 | 0 | 0 | |||
| F13A1 | 0 | 0 | |||
| EZR | 0 | 0 | |||
| EZH2 | 癌症,结直肠癌,弥漫性大B细胞淋巴瘤,滤泡性淋巴瘤,淋巴瘤,黑色素瘤,骨髓增生异常综合征,皮肤黑色素瘤 | 达拉非尼,EZH2 Inhibitor JQEZ5,GSK126,JQEZ5,UNC1999, | 7 | 11 | |
| EZH1 | 0 | 0 | |||
| EYA2 | 0 | 0 | |||
| EXT2 | 0 | 0 | |||
| EXT1 | 0 | 0 | |||
| EXOSC8 | 0 | 0 | |||
| EXOC2 | 0 | 0 | |||
| EXO1 | 0 | 0 | |||
| EWSR1 | 骨尤因肉瘤,骨外黏液样软骨肉瘤 | 舒尼替尼, | 2 | 4 | |
| ETV6 | 急性淋巴细胞白血病,血液肿瘤,骨髓增生异常综合征 | 4 | 5 | ||
| ETV5 | 肺癌,胰腺癌 | 曲美替尼, | 1 | 2 | |
| ETV4 | 肺癌,胰腺癌,前列腺癌 | 曲美替尼, | 1 | 3 | |
| ETV1 | 肺癌,胰腺癌 | 曲美替尼, | 1 | 2 | |
| ETS2 | 非小细胞肺癌 | 顺铂,紫杉醇, | 1 | 1 | |
| ETS1 | 0 | 0 | |||
| ESR2 | 0 | 0 | |||
| ESR1 | 乳腺癌,雌激素受体阳性乳腺癌 | Aromatase Inhibitor,氟维司群,Hormone Therapy,来曲唑片,哌柏西利,帕博西尼,帕博西林, | 他莫昔芬, | 9 | 22 |
| ERRFI1 | 胆管癌,非小细胞肺癌 | EGFR Inhibitor,厄洛替尼, | 2 | 2 | |
| ERMP1 | 0 | 0 | |||
| ERICH3 | 0 | 0 | |||
| ERI1 | 0 | 0 | |||
| ERG | 尤因肉瘤,前列腺癌 | 2 | 2 | ||
| ERF | 0 | 0 | |||
| EREG | 结直肠癌,肺腺癌 | 西妥昔单抗,帕尼单抗, | 1 | 3 | |
| ERCC6 | 0 | 0 | |||
| ERCC5 | 顶叶室管膜瘤 | 1 | 1 | ||
| ERCC4 | 0 | 0 | |||
| ERCC3 | 0 | 0 | |||
| ERCC2 | 非小细胞肺癌,骨肉瘤 | 卡铂,顺铂,紫杉醇, | 1 | 2 | |
| ERCC1 | 膀胱癌,非小细胞肺癌 | Cisplatin Concomitant With Gemcitabine,Cisplatine,Gemcitabine Concomitant With Nedaplatin, | 顺铂, | 3 | 7 |
| ERBB4 | 乳腺癌,头颈部鳞状细胞癌,Her2受体阳性乳腺癌,黑色素瘤 | 厄洛替尼,拉帕替尼,曲妥珠单抗, | 4 | 6 | |
| ERBB3 | 乳腺癌,癌症,结直肠癌,非小细胞肺癌,黑色素瘤,胰管腺癌,尿路上皮癌,葡萄膜黑色素瘤 | 9F7-F11,阿法替尼,AV-203,西妥昔单抗,CP-724714,吉非替尼,拉帕替尼,帕妥珠单抗,司美替尼,曲美替尼,曲妥珠单抗, | 6 | 13 | |
| ERBB2 | 胆道癌,膀胱癌,乳腺癌,结肠癌,结直肠癌,子宫内膜癌,食管癌,胃腺癌,胃食管交界处腺癌,头颈部鳞状细胞癌,肝细胞癌,HER2受体阴性乳腺癌,HER2受体接受治疗或阳性乳腺癌,肺癌,非小细胞肺癌,小细胞癌,卵巢癌,胰腺癌,唾液腺癌,阴囊佩吉特氏病,胃癌,子宫癌,子宫体子宫内膜癌癌,子宫体浆膜腺癌 | A66,Ado-trastuzumab,阿法替尼,AKTi-1/2,博舒替尼,Capecitabin,卡培他滨,Capecitibine,西妥昔单抗,达可替尼,厄洛替尼,吉非替尼,伊布替尼,拉帕替尼,Leucovorin,来那替尼，奈拉替尼,哌柏西利,帕博西尼,帕博西林,帕尼单抗,帕妥珠单抗,Pictilisib,PLATINUM,Torkinib,雷莫芦单抗,西罗莫司,Tgx-221,曲妥珠单抗,XL147 (Pilaralisib), | 氟尿嘧啶,多西他赛,吉西他滨,伊立替康,奥沙利铂,紫杉醇,唑来膦酸, | 42 | 139 |
| EPS15 | 0 | 0 | |||
| EPPK1 | 0 | 0 | |||
| EPOR | 小儿B细胞淋巴母细胞白血病,小儿B淋巴细胞白血病 | JAK-STAT Inhibitors, | 1 | 3 | |
| EPHX1 | 0 | 0 | |||
| EPHB6 | 0 | 0 | |||
| EPHB4 | 结直肠癌 | 贝伐单抗, | 1 | 1 | |
| EPHB2 | 前列腺癌 | 2 | 2 | ||
| EPHB1 | 0 | 0 | |||
| EPHA7 | 0 | 0 | |||
| EPHA6 | 0 | 0 | |||
| EPHA5 | 0 | 0 | |||
| EPHA4 | 0 | 0 | |||
| EPHA3 | 0 | 0 | |||
| EPHA2 | 0 | 0 | |||
| EPHA1 | 0 | 0 | |||
| EPCAM | 林奇综合征 | 1 | 1 | ||
| EPC1 | 0 | 0 | |||
| EPAS1 | 结直肠癌,肾细胞癌 | 帕唑帕尼,培唑帕尼, | 1 | 2 | |
| EP300 | 霍奇金淋巴瘤 | 1 | 1 | ||
| ENOSF1 | 0 | 0 | |||
| ENG | 0 | 0 | |||
| EMSY | 0 | 0 | |||
| EML4 | 0 | 0 | |||
| EME2 | 0 | 0 | |||
| EME1 | 0 | 0 | |||
| ELOC | 0 | 0 | |||
| ELN | 0 | 0 | |||
| ELMO1 | 0 | 0 | |||
| ELL | 0 | 0 | |||
| ELF4 | 0 | 0 | |||
| ELF3 | 0 | 0 | |||
| ELF1 | 0 | 0 | |||
| ELANE | 0 | 0 | |||
| ELAC2 | 0 | 0 | |||
| EIF5A | 0 | 0 | |||
| EIF4G3 | 0 | 0 | |||
| EIF4EBP1 | 结直肠癌,胃腺癌 | Dactolisib,依维莫司,Torkinib,WYE354, | 1 | 2 | |
| EIF4E | 0 | 0 | |||
| EIF4A2 | 0 | 0 | |||
| EIF3A | 0 | 0 | |||
| EIF2AK3 | 0 | 0 | |||
| EIF1AX | 葡萄膜黑色素瘤 | 1 | 1 | ||
| EGR3 | 0 | 0 | |||
| EGFR | 巴雷特腺癌,脑胶质瘤,癌症,宫颈鳞状细胞癌,脊索瘤,慢性髓性白血病,结直肠癌,上皮性卵巢癌,食管鳞状细胞癌,胃腺癌,多形胶质母细胞瘤,头颈鳞状细胞癌,血液学癌,肺腺癌,肺细胞癌。癌,非小细胞肺癌,小细胞肺癌,恶性胶质瘤,恶性间皮瘤,胰腺腺癌,腹膜间皮瘤,皮肤鳞状细胞癌,幕上多形胶质母细胞瘤 | AEE788,阿法替尼,贝伐单抗,博舒替尼,布加替尼,帕尼单抗,西妥昔单抗,卡奈替尼,克唑替尼,CRS/IPHC,达可替尼,EGFR Inhibitor,厄洛替尼,吉非替尼,埃克替尼,拉帕替尼,MEDI4736,来那替尼，奈拉替尼,尼妥珠单抗,奥希替尼,PF 00299804,PLATINUM,西罗莫司,Rintega,Rociletinib,星形孢菌素,Sym004,TAK-788, | 氟尿嘧啶,顺铂,多西他赛,培美曲塞, | 145 | 431 |
| EGFL7 | 0 | 0 | |||
| EGF | 头颈部鳞状细胞癌 | 西妥昔单抗, | 1 | 1 | |
| EEF1A1 | 0 | 0 | |||
| EED | 0 | 0 | |||
| EDNRA | 0 | 0 | |||
| EDC4 | 0 | 0 | |||
| ECT2L | 0 | 0 | |||
| ECSCR | 癌症 | Antiangiogenic Therapy, | 1 | 1 | |
| EBF1 | 0 | 0 | |||
| E2F3 | 0 | 0 | |||
| E2F1 | 0 | 0 | |||
| DYSF | 0 | 0 | |||
| DYNC2H1 | 0 | 0 | |||
| DUX4 | 急性淋巴细胞白血病,小儿B细胞急性淋巴细胞白血病 | 2 | 3 | ||
| DUT | 0 | 0 | |||
| DUSP6 | 癌症 | 曲美替尼, | 1 | 1 | |
| DUSP4 | 0 | 0 | |||
| DUSP27 | 0 | 0 | |||
| DUSP22 | 0 | 0 | |||
| DUSP2 | 0 | 0 | |||
| DTX1 | 0 | 0 | |||
| DSCAM | 0 | 0 | |||
| DROSHA | 癌症,肾威尔姆斯肿瘤 | 2 | 2 | ||
| DRGX | 0 | 0 | |||
| DPYD | 癌症 | 卡培他滨, | 氟尿嘧啶,氟特嗪, | 3 | 3 |
| DPP6 | 0 | 0 | |||
| DOT1L | 0 | 0 |
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