菜单 基因医生

该基因编码一个多囊组（pcg）家族成员。编码蛋白是NuA4组蛋白乙酰转移酶复合物的一个组成部分，可以同时作为转录激活物和阻遏物编码蛋白与细胞凋亡、DNA修复、骨骼肌分化、基因沉默和成人T细胞白血病/淋巴瘤有关选择性剪接导致多个转录变体[由RefSeq提供，2012年12月]
This gene encodes a member of the polycomb group (PcG) family. The encoded protein is a component of the NuA4 histone acetyltransferase complex and can act as both a transcriptional activator and repressor. The encoded protein has been linked to apoptosis, DNA repair, skeletal muscle differentiation, gene silencing, and adult T-cell leukemia/lymphoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]