菜单 基因医生

该基因编码的蛋白是免疫球蛋白γ复合物Fc区的低亲和力受体。编码蛋白参与免疫复合物的吞噬作用和B细胞产生抗体的调节。这种基因的变异可能增加对系统性红斑狼疮（SLE）的敏感性。一些转录变体编码不同的亚型已被发现的这个基因。
The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.