EZH1是一种非特异性多omb抑制复合物-2(PRC2)的组成部分,它介导组蛋白H3(见MIM 602812)lys27(H3K27)的甲基化,并在维持胚胎干细胞多能性和可塑性方面发挥作用(Shen等人,2008年【PubMed 19026780】。【由OMIM提供,2009年3月】
EZH1 is a component of a noncanonical Polycomb repressive complex-2 (PRC2) that mediates methylation of histone H3 (see MIM 602812) lys27 (H3K27) and functions in the maintenance of embryonic stem cell pluripotency and plasticity (Shen et al., 2008 [PubMed 19026780]).[supplied by OMIM, Mar 2009]
基因名: | EZH1 |
别名: | KMT6B |
基因ID: | 2145 |
Chromosome: (GRCh37) | 17 Start: 40852293 End: 40897095 Strand: |
信号通路: |