| 基因名 | 疾病 | 靶向药 | 化疗药 | 基因突变 | 临床解释 |
|---|---|---|---|---|---|
| ARID5B | 0 | 0 | |||
| ARID4B | 0 | 0 | |||
| ARID4A | 0 | 0 | |||
| ARID2 | 0 | 0 | |||
| ARID1B | 0 | 0 | |||
| ARID1A | 透明细胞肾细胞癌,肝癌,卵巢癌,卵巢透明细胞癌,胃癌 | 达沙替尼,GSK126,派姆单抗（帕博利珠单抗）,纳武单抗（纳武利尤单抗）,阿特朱单抗，阿替利珠单抗,索拉非尼, | 4 | 9 | |
| ARHGAP6 | 0 | 0 | |||
| ARHGAP4 | 0 | 0 | |||
| ARHGAP35 | 0 | 0 | |||
| ARHGAP29 | 0 | 0 | |||
| ARHGAP26 | 0 | 0 | |||
| ARFRP1 | 0 | 0 | |||
| ARFGEF2 | 0 | 0 | |||
| ARFGEF1 | 0 | 0 | |||
| AREG | 结直肠癌,头颈部鳞状细胞癌,非小细胞肺癌 | 西妥昔单抗,克唑替尼,帕尼单抗, | 多西他赛, | 1 | 5 |
| ARAP3 | 0 | 0 | |||
| ARAF | 结直肠癌,非小细胞肺癌 | 西妥昔单抗,索拉非尼,曲美替尼,维莫非尼, | 伊立替康, | 2 | 4 |
| AR | 乳腺癌,前列腺癌,唾液腺癌 | 阿比特龙,Abiraterone Acetate,阿帕鲁胺,Dactolisib,Cyproterone Acetate,恩扎鲁胺, | 比卡鲁胺,氟他胺,亮丙瑞林,尼鲁米特, | 6 | 8 |
| Apopt1 | 0 | 0 | |||
| APOL2 | 0 | 0 | |||
| APOE | 0 | 0 | |||
| APOBEC3B | 0 | 0 | |||
| APOB | 0 | 0 | |||
| APLNR | 0 | 0 | |||
| APEX1 | 0 | 0 | |||
| APCDD1 | 0 | 0 | |||
| APC | 结肠癌 | G007-LK,JW55, | 1 | 2 | |
| ANO1 | 0 | 0 | |||
| ANKRD46 | 0 | 0 | |||
| ANKRD36B | 0 | 0 | |||
| ANKRD30B | 0 | 0 | |||
| ANKRD30A | 0 | 0 | |||
| ANKRD27 | 0 | 0 | |||
| ANKRD11 | 0 | 0 | |||
| ANKRA2 | 0 | 0 | |||
| ANK3 | 0 | 0 | |||
| ANK2 | 0 | 0 | |||
| ANGPT2 | 0 | 0 | |||
| ANGPT1 | 0 | 0 | |||
| AMOT | 0 | 0 | |||
| AMER1 | 肾母细胞瘤 | 1 | 1 | ||
| ALOX12B | 0 | 0 | |||
| ALK | 肺泡横纹肌肉瘤,间变性大细胞淋巴瘤,间变性甲状腺癌,乳腺癌,癌症,结肠癌,大肠癌,弥漫性大B细胞淋巴瘤,上皮样炎性肌成纤维细胞肉瘤,结外NK/T细胞淋巴瘤,鼻型,炎性肌成纤维细胞瘤,肺腺泡腺瘤癌,肺腺癌,肺大细胞癌,非小细胞肺癌,神经母细胞瘤,肾细胞癌,皮肤黑色素瘤,阴道肉瘤 | Tanespimycin,17-DMAG,舒尼替尼,阿来替尼，艾乐替尼,Luminespib,AZD3463,布加替尼,色瑞替尼，塞瑞替尼,阿来替尼，艾乐替尼,克唑替尼,恩曲替尼,厄洛替尼,IPI-504,劳拉替尼,PF-2341066,TAE684,WHI-P154, | 4-嘧啶二胺,培美曲塞, | 44 | 175 |
| ALG9 | 0 | 0 | |||
| ALDOC | 0 | 0 | |||
| ALDH2 | 0 | 0 | |||
| ALDH1A2 | 头颈部鳞状细胞癌 | All-trans Retinoic Acid, | 2 | 3 | |
| ALCAM | 结直肠癌 | 氟尿嘧啶, | 1 | 1 | |
| ALB | 0 | 0 | |||
| AKT3 | 乳腺癌,黑色素瘤,三受体阴性乳腺癌 | AKT3 Inhibitor,GSK690693,MK-2206,维莫非尼, | 2 | 5 | |
| AKT2 | 乳腺癌,肺腺癌 | 依维莫司,曲妥珠单抗,凡德他尼, | 2 | 2 | |
| AKT1 | 乳腺癌,癌症,黑色素瘤 | Capivasertib,AZD-5363,达拉非尼,Uprosertib,MK-2206,维莫非尼, | 3 | 9 | |
| AKAP9 | 0 | 0 | |||
| AKAP8 | 0 | 0 | |||
| AK7 | 0 | 0 | |||
| AJUBA | 0 | 0 | |||
| AIP | 0 | 0 | |||
| AHNAK | 0 | 0 | |||
| AGR2 | 乳腺癌 | 他莫昔芬, | 1 | 1 | |
| AGO3 | 0 | 0 | |||
| AGO2 | 0 | 0 | |||
| AGK | 0 | 0 | |||
| AGAP3 | 0 | 0 | |||
| AFF4 | 0 | 0 | |||
| AFF3 | 0 | 0 | |||
| AFF2 | 0 | 0 | |||
| AFF1 | 0 | 0 | |||
| AFDN | 0 | 0 | |||
| AEBP1 | 皮肤黑色素瘤 | 维莫非尼, | 1 | 1 | |
| Adss | 0 | 0 | |||
| ADRB1 | 0 | 0 | |||
| ADH1C | 0 | 0 | |||
| ADH1B | 0 | 0 | |||
| ADH1A | 0 | 0 | |||
| ADGRG4 | 0 | 0 | |||
| ADGRB1 | 0 | 0 | |||
| ADGRA2 | 0 | 0 | |||
| ADCY9 | 0 | 0 | |||
| ADCY1 | 0 | 0 | |||
| ADAMTS6 | 0 | 0 | |||
| ADAMTS5 | 0 | 0 | |||
| ADAMTS12 | 0 | 0 | |||
| ADAM29 | 0 | 0 | |||
| ACYP2 | 0 | 0 | |||
| ACVRL1 | 0 | 0 | |||
| ACVR2A | 0 | 0 | |||
| ACVR1B | 0 | 0 | |||
| ACVR1 | 星形细胞瘤,脑干癌,弥漫性固有桥脑胶质瘤 | 5 | 7 | ||
| ACTL6B | 0 | 0 | |||
| ACTL6A | 0 | 0 | |||
| ACTG2 | 0 | 0 | |||
| ACTG1 | 0 | 0 | |||
| ACTB | 0 | 0 | |||
| ACTA1 | 肺腺癌 | 1 | 1 | ||
| ACSL3 | 0 | 0 | |||
| Acpp | 0 | 0 | |||
| ACOT13 | 0 | 0 | |||
| ACIN1 | 0 | 0 | |||
| ACADSB | 0 | 0 | |||
| ACACA | 0 | 0 | |||
| ABRAXAS1 | 0 | 0 | |||
| ABL2 | 小儿B细胞急性淋巴细胞白血病,小儿B细胞淋巴细胞白血病 | 达沙替尼,Imatinib (STI571), | 1 | 3 | |
| ABL1 | 急性淋巴细胞白血病,急性髓细胞白血病,B细胞成人急性淋巴细胞白血病,慢性髓细胞白血病,非小细胞肺癌,小儿B细胞急性淋巴细胞白血病,小儿B淋巴细胞白血病,前体B淋巴细胞淋巴瘤/白血病 | 阿昔替尼,博舒替尼,达沙替尼,伊马替尼,Imatinib Mesilate,Imatinib Mesylate,Imatinib (STI571),尼洛替尼,高三尖杉酯碱,帕纳替尼/普纳替尼/波纳替尼,Tyrosine Kinase Inhibitor, | 98 | 442 | |
| ABCG2 | 卵巢癌 | 1 | 1 | ||
| ABCC9 | 0 | 0 | |||
| ABCC6 | 0 | 0 | |||
| ABCC4 | 0 | 0 | |||
| ABCC3 | 乳腺癌 | 甲基澳瑞他汀 E,紫杉醇, | 1 | 1 | |
| ABCC2 | 0 | 0 | |||
| ABCC11 | 0 | 0 | |||
| ABCC10 | 非小细胞肺癌 | 紫杉醇, | 1 | 1 | |
| ABCC1 | 0 | 0 | |||
| ABCB4 | 0 | 0 | |||
| ABCB1 | 乳腺癌,肺癌,非小细胞肺癌,卵巢癌 | 卡铂,顺铂,紫杉醇, | 4 | 5 | |
| ABCA8 | 0 | 0 | |||
| ABCA13 | 0 | 0 | |||
| AADAC | 0 | 0 | |||
| A2M | 0 | 0 |
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