菜单 基因医生

该基因编码n-甲基-d-天冬氨酸(nmda)受体信号复合物的一个重要组成部分,该复合物通过将nmda受体的激活与α-氨基-3-羟基-5-甲基-4-异恶唑雷波酸(ampa)受体的转运联系起来,介导突触中的长期增强。编码蛋白包含一个N端GTPase样结构域、一个pleckstrin同源结构域、一个ArfGAP结构域和几个C端ankryn重复结构域[由RefSeq提供,2017年4月]
This gene encodes an essential component of the N-methyl-D-aspartate (NMDA) receptor signaling complex which mediates long-term potentiation in synapses by linking activation of NMDA receptor to alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor trafficking. The encoded protein contains an N-terminal GTPase-like domain, a pleckstrin homology domain, an ArfGAP domain and several C-terminal ankryn repeat domains. [provided by RefSeq, Apr 2017]

基因名:AGAP3
别名:CRAG,AGAP-3,CENTG3,MRIP-1,cnt-g3
基因ID:116988
Chromosome:
(GRCh37)
7 Start: 150782918 End: 150841523 Strand: 
信号通路:  
AGAP3 基因突变与药物