菜单 基因医生

该基因编码c2h2型锌指蛋白zic家族的一个成员。这种核蛋白在左右体轴形成的早期可能起转录因子的作用。该基因的突变导致X连锁内脏异位,包括先天性心脏病和器官中的左右轴缺陷。[由RefSeq提供,2008年7月]
This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This nuclear protein probably functions as a transcription factor in early stages of left-right body axis formation. Mutations in this gene cause X-linked visceral heterotaxy, which includes congenital heart disease and left-right axis defects in organs. [provided by RefSeq, Jul 2008]

基因名:ZIC3
别名:HTX,HTX1,ZNF203,VACTERLX
基因ID:7547
Chromosome:
(GRCh37)
X Start: 136648346 End: 136654259 Strand: 
信号通路:  
ZIC3 基因突变与药物