菜单 基因医生

WNT基因家族由编码分泌信号蛋白的结构相关基因组成这些蛋白与肿瘤发生和一些发育过程有关，包括在胚胎发生过程中调节细胞命运和模式。这个基因是wnt基因家族的一员。它可能与乳腺癌有关，其蛋白信号可能是控制脂肪生成的分子开关在氨基酸水平上，该蛋白与小鼠wnt10b蛋白的一致性为96%。这个基因与另一个家族成员Wnt1在染色体12q13区域聚集在一起。[由RefSeq提供，2008年7月]
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It may be involved in breast cancer, and its protein signaling is likely a molecular switch that governs adipogenesis. This protein is 96% identical to the mouse Wnt10b protein at the amino acid level. This gene is clustered with another family member, WNT1, in the chromosome 12q13 region. [provided by RefSeq, Jul 2008]