菜单 基因医生

该基因是teashirt C2H2型锌指蛋白家族转录因子的成员该基因编码一个含有5个C2H2型锌指、一个同源盒DNA结合区和一个卷曲线圈结构域的蛋白质这种核蛋白被认为是一种转录抑制因子这种基因被认为在乳腺癌和其他类型癌症的发展和进展中起作用。选择性剪接导致编码不同亚型的多个转录变体[由RefSeq提供，2016年12月]
This gene is a member of the teashirt C2H2-type zinc-finger protein family of transcription factors. This gene encodes a protein with five C2H2-type zinc fingers, a homeobox DNA-binding domain and a coiled-coil domain. This nuclear protein is predicted to act as a transcriptional repressor. This gene is thought to play a role in the development and progression of breast and other types of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2016]