菜单 基因医生

该基因编码的蛋白是一种膜蛋白,是甲状腺细胞代谢的主要调控因子。编码蛋白是甲状腺素和甲状腺素的受体,其活性由腺苷酸环化酶介导。这个基因的缺陷是几种甲状腺机能亢进症的原因。已经发现了三个编码不同亚型的转录变体。[由RefSeq提供,2008年12月]
The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]

基因名:TSHR
别名:LGR3,CHNG1,hTSHR-I
基因ID:7253
Chromosome:
(GRCh37)
14 Start: 81421333 End: 81612646 Strand: 
信号通路: 细胞增殖 
TSHR 基因突变与药物