菜单 基因医生

这个基因是一个单羧酸转运体家族的成员。这个家族的成员运输代谢物，如乳酸，丙酮酸和酮体。这个基因编码的蛋白质催化一元羧酸的质子连接运输，对丙酮酸的亲和力最高据报道，与对照组相比，这种蛋白在前列腺癌和结直肠癌标本中的表达更高。选择性剪接导致多个转录变体[由RefSeq提供，2012年7月]
This gene is a member of the monocarboxylate transporter family. Members in this family transport metabolites, such as lactate, pyruvate, and ketone bodies. The protein encoded by this gene catalyzes the proton-linked transport of monocarboxylates and has the highest affinity for pyruvate. This protein has been reported to be more highly expressed in prostate and colorectal cancer specimens when compared to control specimens. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]