该基因编码丝氨酸/苏氨酸激酶rsk(核糖体s6激酶)家族的一个成员。该激酶包含一个激酶催化结构域并磷酸化s6核糖体蛋白和真核翻译起始因子4b(eif4b)。s6的磷酸化导致蛋白质合成和细胞增殖增加。[由RefSeq提供,2015年1月]
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains a kinase catalytic domain and phosphorylates the S6 ribosomal protein and eukaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation. [provided by RefSeq, Jan 2015]
基因名: | RPS6KB2 |
别名: | KLS,SRK,S6K2,S6KB,STK14B,S6KI(2),S6Kbeta,p70S6Kb,P70-beta,S6K-beta2,P70-beta-1,P70-beta-2,p70(S6K)-beta |
基因ID: | 6199 |
Chromosome: (GRCh37) | 11 Start: 67195935 End: 67202879 Strand: |
信号通路: |