该基因编码的蛋白质是一种丝氨酸/苏氨酸激酶,调节胞质分裂、平滑肌收缩、肌动蛋白应力纤维和局灶性粘连的形成以及c-fos血清反应元件的激活这种蛋白质是ROCK1的一种同工酶,是小GTPase Rho的靶标[由RefSeq提供,2008年7月]
The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho. [provided by RefSeq, Jul 2008]
基因名: | ROCK2 |
别名: | ROCK-II |
基因ID: | 9475 |
Chromosome: (GRCh37) | 2 Start: 11319894 End: 11484711 Strand: |
信号通路: |