菜单 基因医生

该基因编码的蛋白质是一种丝氨酸/苏氨酸激酶,调节胞质分裂、平滑肌收缩、肌动蛋白应力纤维和局灶性粘连的形成以及c-fos血清反应元件的激活这种蛋白质是ROCK1的一种同工酶,是小GTPase Rho的靶标[由RefSeq提供,2008年7月]
The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho. [provided by RefSeq, Jul 2008]

基因名:ROCK2
别名:ROCK-II
基因ID:9475
Chromosome:
(GRCh37)
2 Start: 11319894 End: 11484711 Strand: 
信号通路:  
ROCK2 基因突变与药物