该基因编码ras相关GTPase亚家族的一个成员。编码蛋白参与调节与细胞应激相关的p38 mapk依赖性信号级联。该蛋白还与神经生长因子协同促进神经元的发育和再生。交替剪接导致多个转录变体。
This gene encodes a member of a subfamily of Ras-related GTPases. The encoded protein is involved in regulating p38 MAPK-dependent signaling cascades related to cellular stress. This protein also cooperates with nerve growth factor to promote neuronal development and regeneration. Alternate splicing results in multiple transcript variants.
| 基因名： | RIT1 |
| 别名： | NS8,RIBB,RIT,ROC1 |
| 基因ID： | 6016 |
| Chromosome： (GRCh37) | 1 Start: 155867599 End: 155881195 Strand: -1 |
| 信号通路： | |
| 靶向药： | Pictilisib 司美替尼 |
| 化疗药： |
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