菜单 基因医生

该基因编码一小类prenalated蛋白酪氨酸磷酸酶（ptps）的一个成员，该蛋白酪氨酸磷酸酶包含一个ptp结构域和一个特征性的c末端prenalize基序。编码蛋白是一种细胞信号分子，在包括细胞增殖和迁移在内的多种细胞过程中发挥调节作用。这种蛋白也可能参与癌症的发展和转移。这种酪氨酸磷酸酶是一种核蛋白，但可能通过其前酰化基序与质膜结合与该基因相关的假基因位于1、2、5、7、11和X染色体上。[由RefSeq提供，2013年6月]
This gene encodes a member of a small class of prenylated protein tyrosine phosphatases (PTPs), which contain a PTP domain and a characteristic C-terminal prenylation motif. The encoded protein is a cell signaling molecule that plays regulatory roles in a variety of cellular processes, including cell proliferation and migration. The protein may also be involved in cancer development and metastasis. This tyrosine phosphatase is a nuclear protein, but may associate with plasma membrane by means of its prenylation motif. Pseudogenes related to this gene are located on chromosomes 1, 2, 5, 7, 11 and X. [provided by RefSeq, Jun 2013]