菜单 基因医生

这个基因编码一种胰蛋白酶原，它是丝氨酸蛋白酶家族的一员这种酶在大脑和胰腺中表达，对普通的胰蛋白酶抑制剂有抵抗力它对涉及赖氨酸或精氨酸的羧基的肽键具有活性该基因定位于9号染色体上t细胞受体β变异孤儿的位点。已经描述了四个编码不同亚型的转录变体[由RefSeq提供，2010年10月]
This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is expressed in the brain and pancreas and is resistant to common trypsin inhibitors. It is active on peptide linkages involving the carboxyl group of lysine or arginine. This gene is localized to the locus of T cell receptor beta variable orphans on chromosome 9. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2010]