菜单 基因医生

pole4是一种组蛋白折叠蛋白,与其他组蛋白折叠蛋白相互作用,以序列独立的方式结合DNA。这些组蛋白折叠蛋白二聚体结合在较大的酶复合物中,用于DNA转录、复制和包装。
POLE4 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.

基因名:POLE4
别名:YHHQ1,p12
基因ID:56655
Chromosome:
(GRCh37)
2 Start: 75185619 End: 75197255 Strand: 1
信号通路:  
靶向药: 派姆单抗(帕博利珠单抗) 
化疗药:
POLE4 基因突变与药物