菜单 基因医生

该基因编码一个环型泛素e3连接酶lnx家族的成员。这种蛋白可能在血管形态发生和脂肪细胞、成骨细胞和成肌细胞分化中发挥作用该蛋白可被人乳头状瘤病毒E6蛋白靶向降解选择性剪接导致多个转录变体[由RefSeq提供,2014年12月]
This gene encodes a member of the LNX (Ligand of Numb Protein-X) family of RING-type ubiquitin E3 ligases. This protein may function in vascular morphogenesis and the differentiation of adipocytes, osteoblasts and myoblasts. This protein may be targeted for degradation by the human papilloma virus E6 protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

基因名:PDZRN3
别名:LNX3,SEMCAP3,SEMACAP3
基因ID:23024
Chromosome:
(GRCh37)
3 Start: 73431582 End: 73674072 Strand: 
信号通路:  
PDZRN3 基因突变与药物