该基因与wolf-hirschhorn综合征候选基因1相关，编码一个具有pwp（脯氨酸-色氨酸-色氨酸-脯氨酸）结构域的蛋白质。该蛋白在赖氨酸残基4和27处甲基化组蛋白H3，抑制基因转录。已经描述了两种可选的拼接变体。[由RefSeq提供，2015年5月]
This gene is related to the Wolf-Hirschhorn syndrome candidate-1 gene and encodes a protein with PWWP (proline-tryptophan-tryptophan-proline) domains. This protein methylates histone H3 at lysine residues 4 and 27, which represses gene transcription. Two alternatively spliced variants have been described. [provided by RefSeq, May 2015]
| 基因名： | NSD3 |
| 别名： | KMT3F,KMT3G,WHISTLE,WHSC1L1,pp14328 |
| 基因ID： | 54904 |
| Chromosome： (GRCh37) | 8 Start: 38127217 End: 38239872 Strand: |
| 信号通路： |
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