| 基因名 | 疾病 | 靶向药 | 化疗药 | 基因突变 | 临床解释 |
|---|---|---|---|---|---|
| U2AF1 | 急性髓性白血病,骨髓增生异常综合征,骨髓纤维化 | 3 | 8 | ||
| UBE2D2 | 0 | 0 | |||
| UBE2E3 | 0 | 0 | |||
| UBE3C | 0 | 0 | |||
| UBR5 | 0 | 0 | |||
| UGT1A | 结直肠癌 | Ganetespib, | 1 | 1 | |
| UGT1A1 | 癌症 | 贝利司他, | 2 | 2 | |
| UGT1A8 | 0 | 0 | |||
| UGT1A9 | 0 | 0 | |||
| ULK4 | 0 | 0 | |||
| UMPS | 0 | 0 | |||
| UNC5D | 0 | 0 | |||
| UPF1 | 0 | 0 | |||
| UPF2 | 0 | 0 | |||
| UPF3B | 0 | 0 | |||
| UROD | 0 | 0 | |||
| USH2A | 0 | 0 | |||
| USHBP1 | 0 | 0 | |||
| USP1 | 0 | 0 | |||
| USP12 | 0 | 0 | |||
| USP34 | 0 | 0 | |||
| USP48 | 0 | 0 | |||
| USP6 | 0 | 0 | |||
| USP8 | 0 | 0 | |||
| VAMP2 | 0 | 0 | |||
| VDAC2 | 0 | 0 | |||
| VEGFA | 结直肠癌,多形性胶质母细胞瘤,卵巢癌,胃癌 | 贝伐单抗,厄洛替尼,L-Folinic Acid, | 氟尿嘧啶,伊立替康, | 2 | 4 |
| VEGFB | 0 | 0 | |||
| VEGFC | 0 | 0 | |||
| VEZF1 | 0 | 0 | |||
| VHL | 肾上腺嗜铬细胞瘤,丘瓦什红细胞增多症,透明细胞肾细胞癌,真性红细胞增多症,肾癌,肾细胞癌,von hippel-lindau病 | 依维莫司,帕唑帕尼,培唑帕尼,芦可替尼/鲁索利替尼/鲁索替尼,舒尼替尼,西罗莫司,VEGF Inhibition, | 624 | 1527 | |
| VIM | 0 | 0 | |||
| VPS37A | 卵巢癌 | 西妥昔单抗, | 1 | 1 | |
| VSIG10 | 0 | 0 | |||
| VTCN1 | 0 | 0 | |||
| WAS | 0 | 0 | |||
| WASF3 | 0 | 0 | |||
| WDR5 | 0 | 0 | |||
| WDR90 | 0 | 0 | |||
| WDTC1 | 0 | 0 | |||
| WEE1 | 弥漫性固有桥脑胶质瘤,非小细胞肺癌 | AZD1775,PLATINUM, | 吉西他滨, | 2 | 3 |
| WEE2 | 0 | 0 | |||
| WHSC1 | 0 | 0 | |||
| WHSC1L1 | 0 | 0 | |||
| WIPF1 | 0 | 0 | |||
| WISP3 | 0 | 0 | |||
| WNK1 | 0 | 0 | |||
| WNT1 | 0 | 0 | |||
| WNT10A | 0 | 0 | |||
| WNT10B | 0 | 0 | |||
| WNT5A | 0 | 0 | |||
| WNT6 | 0 | 0 | |||
| WNT7B | 0 | 0 | |||
| WRN | 0 | 0 | |||
| WSCD2 | 0 | 0 | |||
| WT1 | 急性髓性白血病 | 阿糖胞苷,柔红霉素, | 2 | 11 | |
| WWC3 | 0 | 0 | |||
| WWOX | 0 | 0 | |||
| WWP1 | 0 | 0 | |||
| WWP2 | 0 | 0 | |||
| WWTR1 | 上皮样血管内皮瘤 | 1 | 1 | ||
| XBP1 | 0 | 0 | |||
| XIAP | 0 | 0 | |||
| XIRP2 | 0 | 0 | |||
| XPA | 0 | 0 | |||
| XPC | 0 | 0 | |||
| XPCC1 | 0 | 0 | |||
| XPO1 | 0 | 0 | |||
| XRCC1 | 宫颈癌,非小细胞肺癌 | 卡铂,顺铂,多西他赛,吉西他滨,长春瑞滨, | 2 | 3 | |
| XRCC2 | 0 | 0 | |||
| XRCC3 | 0 | 0 | |||
| YAP1 | 食管癌 | 氟尿嘧啶,多西他赛,维替泊芬, | 1 | 2 | |
| YBX1 | 0 | 0 | |||
| YES1 | 0 | 0 | |||
| YWHAZ | 0 | 0 | |||
| YY1AP1 | 0 | 0 | |||
| ZAN | 0 | 0 | |||
| ZBBX | 0 | 0 | |||
| ZBTB16 | 0 | 0 | |||
| ZBTB2 | 0 | 0 | |||
| ZC3H11A | 0 | 0 | |||
| ZC3H7B | 0 | 0 | |||
| ZDHHC17 | 0 | 0 | |||
| ZEB1 | 套细胞淋巴瘤 | 阿糖胞苷,多柔比星,吉西他滨,盐霉素, | 1 | 2 | |
| ZFHX3 | 0 | 0 | |||
| ZFHX4 | 0 | 0 | |||
| ZFP36L1 | 0 | 0 | |||
| ZFP36L2 | 0 | 0 | |||
| ZFPM2 | 0 | 0 | |||
| ZIC1 | 0 | 0 | |||
| ZIC3 | 0 | 0 | |||
| ZIC4 | 0 | 0 | |||
| ZIM2 | 0 | 0 | |||
| ZMAT3 | 0 | 0 | |||
| ZMYM3 | 0 | 0 | |||
| ZMYM4 | 0 | 0 | |||
| ZNF148 | 0 | 0 | |||
| ZNF2 | 0 | 0 | |||
| ZNF217 | 0 | 0 | |||
| ZNF367 | 0 | 0 | |||
| ZNF384 | 0 | 0 | |||
| ZNF423 | 0 | 0 | |||
| ZNF521 | 0 | 0 | |||
| ZNF536 | 0 | 0 | |||
| ZNF638 | 0 | 0 | |||
| ZNF703 | 0 | 0 | |||
| ZNF711 | 0 | 0 | |||
| ZNF750 | 0 | 0 | |||
| ZNF770 | 0 | 0 | |||
| ZNF804A | 0 | 0 | |||
| ZNF804B | 0 | 0 | |||
| ZNF805 | 0 | 0 | |||
| ZNF814 | 0 | 0 | |||
| ZNF831 | 0 | 0 | |||
| ZNF91 | 0 | 0 | |||
| ZNRF3 | 0 | 0 | |||
| ZRSR2 | 0 | 0 | |||
| ZZZ3 | 0 | 0 |
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