菜单 基因医生

CHD家族蛋白的特征是存在染色质(染色质组织修饰剂)结构域和SNF2相关解旋酶/ ATPase结构域。 CHD基因可能通过修饰染色质结构来改变基因表达,从而改变转录设备对其染色体DNA模板的访问。 已经发现该基因的编码不同同工型的剪接的转录变体。 [由RefSeq提供,2008年7月]
The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
 

基因名:CHD2
别名:EEOC
基因ID:1106
Chromosome:
(GRCh37)
15 Start: 93442286 End: 93571237 Strand: 
信号通路: DNA修饰及其它  基因组不稳定 
CHD2 基因突变与药物