| 基因名 | 疾病 | 靶向药 | 化疗药 | 基因突变 | 临床解释 |
|---|---|---|---|---|---|
| TP53 | 急性髓细胞白血病,肾上腺皮质癌,乳腺癌,癌症,宫颈癌,慢性淋巴细胞白血病,CLL/SLL,结直肠癌,食管癌,食管鳞状细胞癌,胃腺癌,头颈鳞状细胞癌,白血病,李夫琅梅尼综合征,肺腺癌癌细胞瘤,肺癌,非小细胞肺癌,淋巴瘤,骨髓增生异常综合征,骨髓瘤,神经母细胞瘤,少突胶质瘤,口腔鳞状细胞癌,卵巢癌,前体B淋巴细胞淋巴瘤/白血病,唾液腺粘液腺癌,肉瘤,皮肤鳞状细胞癌,胃癌胃癌,华登斯特巨球蛋白血症 | Adjuvant Chemotherapy,阿仑单抗,AMGMDS3,硼替佐米,卡培他滨,西妥昔单抗,Chemotherapy,EAP Protocol,Nutlin-3a,帕唑帕尼,培唑帕尼,RG7112,司美替尼,维莫非尼,维奈妥拉/维耐托克, | 卡铂,顺铂,多西他赛,多柔比星,依托泊苷,丝裂霉素,奥沙利铂,他莫昔芬, | 53 | 138 |
| TERT | Acral扁豆状黑色素瘤,脑胶质瘤,透明细胞肾细胞癌,多形胶质母细胞瘤,乳头状甲状腺癌,儿童低级别胶质瘤（PLGG）,皮肤黑色素瘤,甲状腺癌 | I-131,U0126, | 5 | 15 | |
| TYMS | 癌症,结直肠癌,胃腺癌,肺腺癌,非小细胞肺癌,前列腺癌 | 氟尿嘧啶,伊立替康,甲氨蝶呤,培美曲塞,雷替曲塞, | 5 | 8 | |
| TSC1 | 膀胱癌,浸润性膀胱移行细胞癌,非小细胞肺癌,肾细胞癌,结节性硬化症 | 依维莫司,MTOR Inhibitors,西罗莫司, | 3 | 8 | |
| TET2 | 急性髓性白血病,骨髓增生异常综合征 | 1 | 6 | ||
| TOP1 | 结直肠癌,卵巢癌 | 卡铂,环磷酰胺,伊立替康,拓扑替康, | 2 | 3 | |
| TSC2 | 肾细胞癌,甲状腺癌,结节性硬化 | 依维莫司,MTOR Inhibitors, | 2 | 3 | |
| TIMP1 | 乳腺癌 | 氟维司群, | 紫杉醇, | 1 | 2 |
| TUBB3 | 乳腺癌,癌症 | Taxane, | 紫杉醇, | 1 | 2 |
| TTF1 | 肺腺癌 | 1 | 1 | ||
| TF | 黑色素瘤 | 维莫非尼, | 1 | 1 | |
| TFF3 | 乳腺癌 | 氨鲁米特,他莫昔芬, | 1 | 1 | |
| TGFA | 头颈部鳞状细胞癌 | 1 | 1 | ||
| TGFBR3 | 前列腺癌 | 1 | 1 | ||
| THBS2 | 结直肠癌 | 1 | 1 | ||
| TOP2A | 乳腺癌 | 多柔比星, | 1 | 1 | |
| TPT1 | 黑色素瘤 | Sertraline (INN), | 1 | 1 | |
| TSPYL1 | 前列腺癌 | 1 | 1 | ||
| TLK2 | 乳腺癌 | GF109203X,Go6983, | 1 | 1 | |
| TBK1 | 黑色素瘤 | AZ909,司美替尼, | 1 | 1 | |
| TAF1 | 0 | 0 | |||
| TGFBR2 | 0 | 0 | |||
| TNFRSF14 | 0 | 0 | |||
| TEK | 0 | 0 | |||
| TMEM127 | 0 | 0 | |||
| TSHR | 0 | 0 | |||
| TNFAIP3 | 0 | 0 | |||
| TMPRSS2 | 0 | 0 | |||
| TPMT | 0 | 0 | |||
| TBX3 | 0 | 0 | |||
| TNF | 0 | 0 | |||
| TAP1 | 0 | 0 | |||
| TAP2 | 0 | 0 | |||
| TCF3 | 0 | 0 | |||
| TCF4 | 0 | 0 | |||
| TCF7L2 | 0 | 0 | |||
| TDO2 | 0 | 0 | |||
| TEKT4 | 0 | 0 | |||
| TERC | 0 | 0 | |||
| TET1 | 0 | 0 | |||
| TFE3 | 0 | 0 | |||
| TGFBR1 | 0 | 0 | |||
| TIPARP | 0 | 0 | |||
| TLR4 | 0 | 0 | |||
| TNFRSF11A | 0 | 0 | |||
| TNFSF11 | 0 | 0 | |||
| TNKS | 0 | 0 | |||
| TNKS2 | 0 | 0 | |||
| TOP3A | 0 | 0 | |||
| TP53BP1 | 0 | 0 | |||
| TP63 | 0 | 0 | |||
| TPM3 | 0 | 0 | |||
| TRAF2 | 0 | 0 | |||
| TRAF5 | 0 | 0 | |||
| TRAF7 | 0 | 0 | |||
| TRRAP | 0 | 0 | |||
| TUBA1A | 0 | 0 | |||
| TUBB | 0 | 0 | |||
| TUBD1 | 0 | 0 | |||
| TUBE1 | 0 | 0 | |||
| TUBG1 | 0 | 0 | |||
| TYK2 | 0 | 0 | |||
| TYRO3 | 0 | 0 | |||
| TCEB1 | 0 | 0 | |||
| TACC2 | 0 | 0 | |||
| TACC3 | 0 | 0 | |||
| TAF15 | 0 | 0 | |||
| TAF1L | 0 | 0 | |||
| TAGAP | 0 | 0 | |||
| TAL1 | 0 | 0 | |||
| TBC1D8B | 0 | 0 | |||
| TBL1XR1 | 0 | 0 | |||
| TBL3 | 0 | 0 | |||
| TBP | 0 | 0 | |||
| TBX15 | 0 | 0 | |||
| TBX22 | 0 | 0 | |||
| TCERG1 | 0 | 0 | |||
| TCF12 | 0 | 0 | |||
| TCL1A | 0 | 0 | |||
| TCP11 | 0 | 0 | |||
| TDG | 0 | 0 | |||
| Tec | 0 | 0 | |||
| TECPR2 | 0 | 0 | |||
| TENM3 | 0 | 0 | |||
| TENT5C | 0 | 0 | |||
| TEX12 | 0 | 0 | |||
| TFDP1 | 0 | 0 | |||
| TFDP2 | 0 | 0 | |||
| TFG | 0 | 0 | |||
| TG | 0 | 0 | |||
| TGFB1 | 0 | 0 | |||
| TGM2 | 0 | 0 | |||
| THADA | 0 | 0 | |||
| THBS1 | 0 | 0 | |||
| THRAP3 | 0 | 0 | |||
| THRB | 0 | 0 | |||
| TIE1 | 0 | 0 | |||
| TIMM8B | 0 | 0 | |||
| TJP1 | 0 | 0 | |||
| TLE1 | 0 | 0 | |||
| TLL1 | 0 | 0 | |||
| TLL2 | 0 | 0 | |||
| TLX3 | 0 | 0 | |||
| TMEM132D | 0 | 0 | |||
| TMEM67 | 0 | 0 | |||
| TMPRSS15 | 0 | 0 | |||
| TNFRSF17 | 0 | 0 | |||
| TNFRSF19 | 0 | 0 | |||
| TNFRSF8 | 0 | 0 | |||
| TNFSF13B | 0 | 0 | |||
| TNK2 | 0 | 0 | |||
| TNN | 0 | 0 | |||
| TNPO1 | 0 | 0 | |||
| TNR | 0 | 0 | |||
| TNRC18 | 0 | 0 | |||
| TOE1 | 0 | 0 | |||
| TOP2B | 0 | 0 | |||
| TOPBP1 | 0 | 0 | |||
| TP73 | 0 | 0 | |||
| TPH1 | 0 | 0 | |||
| TPR | 0 | 0 | |||
| TPX2 | 0 | 0 | |||
| TRA2A | 0 | 0 | |||
| TRAP1 | 0 | 0 | |||
| TRERF1 | 0 | 0 | |||
| TRIM24 | 0 | 0 | |||
| TRIM58 | 0 | 0 | |||
| TRIO | 0 | 0 | |||
| TRPC5 | 0 | 0 | |||
| TRPS1 | 0 | 0 | |||
| TSHZ2 | 0 | 0 | |||
| TSHZ3 | 0 | 0 | |||
| TSN | 0 | 0 | |||
| TTL | 0 | 0 | |||
| TUBA3C | 0 | 0 | |||
| TUBB4A | 0 | 0 | |||
| TUBB4B | 0 | 0 | |||
| TUBB6 | 0 | 0 | |||
| TUSC3 | 0 | 0 | |||
| TWIST1 | 0 | 0 | |||
| TXNIP | 0 | 0 | |||
| TXNRD1 | 0 | 0 | |||
| TYMP | 0 | 0 | |||
| TYR | 0 | 0 | |||
| TYRP1 | 0 | 0 |
Copyright © 2020 基因医生
京ICP备13051264号-65 
京公网安备
11010802036025号