| 基因名 | 疾病 | 靶向药 | 化疗药 | 基因突变 | 临床解释 |
|---|---|---|---|---|---|
| RET | 乳腺癌,癌症,雌激素受体阴性乳腺癌,胃肠道间质瘤,肺腺癌,肺癌,非小细胞肺癌,乳头状腺癌,乳头状甲状腺癌,甲状腺癌,甲状腺髓样癌 | 阿来替尼，艾乐替尼,阿昔替尼,AZD1480,卡博替尼,依维莫司,INK128,仑伐替尼 乐伐替尼,塞尔帕替尼,尼达尼布,NVP-AST487,帕纳替尼/普纳替尼/波纳替尼,瑞戈非尼,索拉非尼,舒尼替尼,凡德他尼, | 莫特塞尼, | 13 | 36 |
| ROS1 | 支气管肺泡腺癌,癌,大肠癌,多形胶质母细胞瘤,炎性肌成纤维细胞瘤,肺腺癌,非小细胞肺癌 | AZD3463,布加替尼,卡博替尼,色瑞替尼，塞瑞替尼,克唑替尼,恩曲替尼,Foretinib,吉非替尼,劳拉替尼,TAE684, | 12 | 31 | |
| RUNX1 | 急性淋巴细胞性白血病,急性髓性白血病,骨髓增生异常综合征 | 阿糖胞苷, | 7 | 13 | |
| RB1 | 乳腺癌,雌激素受体阳性乳腺癌,多形胶质母细胞瘤,非小细胞肺癌,小细胞肺癌,胰腺腺癌,膀胱癌 | 阿培利司,Chemotherapy,丝裂霉素C,哌柏西利,帕博西尼,帕博西林,瑞博西尼, | 氟尿嘧啶,多柔比星,吉西他滨, | 7 | 9 |
| RRM1 | 非小细胞肺癌,胰腺癌 | Cisplatine,PLATINUM, | 顺铂,多西他赛,吉西他滨,吉西他滨,顺铂,紫杉醇,长春瑞滨, | 2 | 9 |
| RICTOR | 胃腺癌,肺腺癌,小细胞肺癌 | AZD2014,AZD8055,CC-223,INK128,Sapanisertib, | 1 | 3 | |
| RAF1 | 黑色素瘤,皮肤黑色素瘤 | 索拉非尼,维莫非尼, | 卡铂,紫杉醇, | 2 | 2 |
| RIT1 | 子宫内膜癌,肺腺癌 | Pictilisib,司美替尼, | 2 | 2 | |
| REL | 弥漫性大B细胞淋巴瘤 | 1 | 1 | ||
| RHOA | 胃癌 | 1 | 1 | ||
| RAC1 | 黑色素瘤 | 达拉非尼,维莫非尼, | 1 | 1 | |
| RAD23B | 肉瘤 | 伏立诺他, | 1 | 1 | |
| RAD51D | 乳腺癌 | 1 | 1 | ||
| RASA1 | 非小细胞肺癌 | 曲美替尼, | 1 | 1 | |
| RHEB | 肾癌 | 西罗莫司, | 1 | 1 | |
| RPS6 | 胃腺癌 | 依维莫司, | 1 | 1 | |
| RRM2 | 胰腺癌 | 吉西他滨, | 1 | 1 | |
| RAD50 | 输尿管小细胞癌 | AZD7762, | 伊立替康, | 1 | 1 |
| RSF1 | 乳腺癌 | 他莫昔芬, | 1 | 1 | |
| ROBO4 | 癌症 | Antiangiogenic Therapy, | 1 | 1 | |
| RARA | 0 | 0 | |||
| RNF43 | 0 | 0 | |||
| RPTOR | 0 | 0 | |||
| RAD51 | 0 | 0 | |||
| RANBP2 | 0 | 0 | |||
| RAD51C | 0 | 0 | |||
| RUNX1T1 | 0 | 0 | |||
| RAB35 | 0 | 0 | |||
| RAC2 | 0 | 0 | |||
| RAD51B | 0 | 0 | |||
| RAD52 | 0 | 0 | |||
| RAD54L | 0 | 0 | |||
| RARB | 0 | 0 | |||
| RNASEL | 0 | 0 | |||
| ROCK1 | 0 | 0 | |||
| RPA1 | 0 | 0 | |||
| RPS6KB1 | 0 | 0 | |||
| RSPO2 | 0 | 0 | |||
| RUNX3 | 0 | 0 | |||
| RXRA | 0 | 0 | |||
| RYBP | 0 | 0 | |||
| RAD21 | 0 | 0 | |||
| RARG | 0 | 0 | |||
| RBBP8 | 0 | 0 | |||
| RBM10 | 0 | 0 | |||
| RECQL | 0 | 0 | |||
| RECQL4 | 0 | 0 | |||
| RELA | 0 | 0 | |||
| RHBDF2 | 0 | 0 | |||
| RINT1 | 0 | 0 | |||
| RPS6KB2 | 0 | 0 | |||
| RBI | 0 | 0 | |||
| RABGAP1L | 0 | 0 | |||
| RAC3 | 0 | 0 | |||
| RAD54B | 0 | 0 | |||
| RAI14 | 0 | 0 | |||
| RASGEF1A | 0 | 0 | |||
| RASGRP1 | 0 | 0 | |||
| RASSF1 | 0 | 0 | |||
| RASSF8 | 0 | 0 | |||
| RBL1 | 0 | 0 | |||
| RBM27 | 0 | 0 | |||
| REEP5 | 0 | 0 | |||
| REG3A | 0 | 0 | |||
| RELN | 0 | 0 | |||
| REV1 | 0 | 0 | |||
| REV3L | 0 | 0 | |||
| RFC1 | 0 | 0 | |||
| RFC4 | 0 | 0 | |||
| RGPD3 | 0 | 0 | |||
| RGS3 | 0 | 0 | |||
| RHOH | 0 | 0 | |||
| RHOT1 | 0 | 0 | |||
| RHPN1 | 0 | 0 | |||
| RIC1 | 0 | 0 | |||
| RIPK2 | 0 | 0 | |||
| RIPK4 | 0 | 0 | |||
| RMI2 | 0 | 0 | |||
| RNF19A | 0 | 0 | |||
| RNF213 | 0 | 0 | |||
| ROBO1 | 0 | 0 | |||
| ROBO2 | 0 | 0 | |||
| ROBO3 | 0 | 0 | |||
| ROCK2 | 0 | 0 | |||
| RP1L1 | 0 | 0 | |||
| RPA4 | 0 | 0 | |||
| RPGR | 0 | 0 | |||
| RPL11 | 0 | 0 | |||
| RPL22 | 0 | 0 | |||
| RPL35A | 0 | 0 | |||
| RPL5 | 0 | 0 | |||
| RPP30 | 0 | 0 | |||
| RPS10 | 0 | 0 | |||
| RPS14 | 0 | 0 | |||
| RPS17 | 0 | 0 | |||
| RPS19 | 0 | 0 | |||
| RPS24 | 0 | 0 | |||
| RPS26 | 0 | 0 | |||
| RPS29 | 0 | 0 | |||
| RPS6KA1 | 0 | 0 | |||
| RPS6KA3 | 0 | 0 | |||
| RPS6KA4 | 0 | 0 | |||
| RPS7 | 0 | 0 | |||
| RRAGC | 0 | 0 | |||
| RRAS | 0 | 0 | |||
| RRAS2 | 0 | 0 | |||
| RRP1B | 0 | 0 | |||
| RSPO3 | 0 | 0 | |||
| RTEL1 | 0 | 0 | |||
| RUFY4 | 0 | 0 | |||
| RUNX2 | 0 | 0 | |||
| RXRB | 0 | 0 | |||
| RXRG | 0 | 0 | |||
| RYR1 | 0 | 0 | |||
| RYR2 | 0 | 0 | |||
| RYR3 | 0 | 0 |
Copyright © 2020 基因医生
京ICP备13051264号-65 
京公网安备
11010802036025号