菜单 基因医生

SRY相关的HMG-box(SOX)基因编码一个DNA结合蛋白家族,该家族含有79个氨基酸HMG(高迁移率基团)结构域,与SRY蛋白(MIM 480000)的DNA结合HMG-box具有至少50%的序列同源性根据hmg域内外的序列相似性,sox蛋白被分成6个亚群。有关sox基因的其他背景信息,请参见sox1(mim 602148)。[由omim提供,2004年4月]
SRY-related HMG-box (SOX) genes encode a family of DNA-binding proteins containing a 79-amino acid HMG (high mobility group) domain that shares at least 50% sequence identity with the DNA-binding HMG box of the SRY protein (MIM 480000). SOX proteins are divided into 6 subgroups based on sequence similarity within and outside of the HMG domain. For additional background information on SOX genes, see SOX1 (MIM 602148).[supplied by OMIM, Apr 2004]

基因名:SOX21
别名:SOX25
基因ID:11166
Chromosome:
(GRCh37)
13 Start: 95361876 End: 95364389 Strand: 
信号通路:  
SOX21 基因突变与药物