菜单 基因医生

该基因编码的蛋白是一种GTP酶,属于小GTP结合蛋白的ras超家族。这个超家族的成员似乎调节着各种各样的细胞事件,包括控制细胞生长、细胞骨架重组和蛋白激酶的激活。两个编码不同亚型的转录变体已经被发现。
The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene.

基因名:RAC1
别名:MIG5,Rac-1,TC-25,p21-Rac1
基因ID:5879
Chromosome:
(GRCh37)
7 Start: 6414154 End: 6443608 Strand: 1
信号通路: 细胞增殖  免疫相关  侵袭和转移  肿瘤干细胞 
靶向药: 达拉非尼  维莫非尼 
化疗药:
RAC1 基因突变与药物