菜单 基因医生

该基因编码的蛋白质是丝氨酸/苏氨酸蛋白磷酸酶4复合物的调节亚单位。这种复合物除了能有效修复DNA双链断裂外,还参与中心体微管的组织和剪接体snrnp的加工已经发现了一些编码不同亚型的转录变体。[由RefSeq提供,2015年12月]
The protein encoded by this gene is a regulatory subunit of the serine/threonine-protein phosphatase 4 complex. In addition to being required for efficient DNA double strand break repair, this complex plays a role in organization of microtubules at centrosomes and processing of spliceosomal snRNPs. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]

基因名:PPP4R2
别名:PP4R2
基因ID:151987
Chromosome:
(GRCh37)
3 Start: 73045985 End: 73118349 Strand: 
信号通路:  
PPP4R2 基因突变与药物