菜单 基因医生

该基因编码的蛋白是一种质膜蛋白,催化胞外核苷酸转化为膜渗透性核苷。编码蛋白被用作淋巴细胞分化的决定因素。这种基因的缺陷会导致关节和动脉钙化。两个编码不同亚型的转录变体已经被发现。
The protein encoded by this gene is a plasma membrane protein that catalyzes the conversion of extracellular nucleotides to membrane-permeable nucleosides. The encoded protein is used as a determinant of lymphocyte differentiation. Defects in this gene can lead to the calcification of joints and arteries. Two transcript variants encoding different isoforms have been found for this gene.

基因名:NT5E
别名:CALJA,CD73,E5NT,NT,NT5,NTE,eN,eNT
基因ID:4907
Chromosome:
(GRCh37)
6 Start: 86159809 End: 86205500 Strand: 1
信号通路:  
靶向药: 西妥昔单抗 
化疗药:
NT5E 基因突变与药物