菜单 基因医生

该基因编码的蛋白是丝氨酸/苏氨酸蛋白激酶家族的成员。该激酶包含一个双亮氨酸拉链基序,并已证明通过其亮氨酸拉链基序形成二聚体/低聚物。该激酶能磷酸化并激活mapk8/jnk,map2k7/mkk7,提示其在jnk信号通路中的作用。[由RefSeq提供,2008年7月]
The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase contains a dual leucine-zipper motif, and has been shown to form dimers/oligomers through its leucine-zipper motif. This kinase can phosphorylate and activate MAPK8/JNK, MAP2K7/MKK7, which suggests a role in the JNK signaling pathway. [provided by RefSeq, Jul 2008]

基因名:MAP3K13
别名:LZK,MLK,MEKK13
基因ID:9175
Chromosome:
(GRCh37)
3 Start: 185000729 End: 185206882 Strand: 
信号通路:  
MAP3K13 基因突变与药物