菜单 基因医生

该基因属于黑色素瘤相关抗原(MAGE)超家族的非CT(非癌症/睾丸)亚群。编码蛋白可能与细胞凋亡、细胞周期停滞、生长抑制或细胞分化有关。该蛋白可能通过STAT1α(信号转导子和转录激活子1α)途径参与ATRA(全反式维甲酸)信号传导。
This gene belongs to the non-CT (non cancer/testis) subgroup of the melanoma-associated antigen (MAGE) superfamily. The encoded protein is likely associated with apoptosis, cell cycle arrest, growth inhibition or cell differentiation. The protein may be involved in the atRA (all-trans retinoic acid) signaling through the STAT1-alpha (signal transducer and activator of transcription 1-alpha) pathway.

基因名:MAGEH1
别名:APR-1,APR1,MAGEH
基因ID:28986
Chromosome:
(GRCh37)
X Start: 55478538 End: 55479998 Strand: 1
信号通路:  
靶向药:
化疗药: 吉西他滨 
MAGEH1 基因突变与药物