菜单 基因医生

irf2编码干扰素调节因子2,是干扰素调节转录因子(irf)家族的成员。irf2竞争性地抑制irf1介导的干扰素α和β的转录激活,可能还有其他利用irf1进行转录激活的基因。然而,irf2也可以作为组蛋白h4的转录激活物。[由RefSeq提供,2008年7月]
IRF2 encodes interferon regulatory factor 2, a member of the interferon regulatory transcription factor (IRF) family. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. However, IRF2 also functions as a transcriptional activator of histone H4. [provided by RefSeq, Jul 2008]

基因名:IRF2
别名:IRF-2
基因ID:3660
Chromosome:
(GRCh37)
4 Start: 185308867 End: 185395734 Strand: 
信号通路: 凋亡抑制 
IRF2 基因突变与药物