菜单 基因医生

这个基因(IFNGR2)编码γ干扰素受体的非配体结合β链人干扰素γ受体是ifngr1和ifngr2的异二聚体。IFNGR2缺陷是孟德尔对分枝杆菌病(MSMD)易感性的原因,也被称为家族性播散性非典型分枝杆菌感染msmd是一种具有常染色体隐性遗传、常染色体显性遗传或x连锁遗传的遗传异质性疾病。[由RefSeq提供,2008年7月]
This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance. [provided by RefSeq, Jul 2008]

基因名:IFNGR2
别名:AF-1,IFGR2,IMD28,IFNGT1
基因ID:3460
Chromosome:
(GRCh37)
21 Start: 34775202 End: 34809828 Strand: 
信号通路:  
IFNGR2 基因突变与药物