菜单 基因医生

这个基因编码一种可溶性细胞因子,它是Ⅱ型干扰素的一个成员。编码的蛋白质由先天免疫系统和适应性免疫系统的细胞分泌。活性蛋白是一种与干扰素γ受体结合的同二聚体,它触发细胞对病毒和微生物感染的反应。这种基因突变与病毒、细菌和寄生虫感染以及一些自身免疫疾病的易感性增加有关。[由RefSeq提供,2015年12月]
This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases. [provided by RefSeq, Dec 2015]

基因名:IFNG
别名:IFG,IFI
基因ID:3458
Chromosome:
(GRCh37)
12 Start: 68548550 End: 68553521 Strand: 
信号通路:  
IFNG 基因突变与药物