菜单 基因医生

该基因编码一种属于gata转录因子家族的蛋白质。该蛋白含有两个gata型锌指,是t细胞发育的重要调节因子,在内皮细胞生物学中具有重要作用。该基因缺陷是甲状旁腺机能减退伴感音神经性耳聋和肾发育不良的原因。[由RefSeq提供,2009年11月]
This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia. [provided by RefSeq, Nov 2009]

基因名:GATA3
别名:HDR,HDRS
基因ID:2625
Chromosome:
(GRCh37)
10 Start: 8087294 End: 8117164 Strand: 
信号通路: 肿瘤干细胞 
GATA3 基因突变与药物