菜单 基因医生

这个基因可以编码一种线粒体酶,这种酶被认为可以将L-岩藻酸盐转化为2-酮-3-脱氧-L-岩藻酸盐。该位点最初被鉴定为相邻胸苷酸合成酶基因反义rna的来源。该位点的剪接变异体可能包含一个与胸苷酸合成酶(TS)RNA的3'UTR和末端内含子互补的3'外显子,并可能下调TS的表达[由RefSeq提供,2017年8月]
This gene can encode a mitochondrial enzyme that is thought to convert L-fuconate to 2-keto-3-deoxy-L-fuconate. This locus was originally identified as the source of antisense RNAs of the adjacent thymidylate synthase gene. Splice variants at this locus may contain an alternate 3' exon that is complementary to the 3'UTR and terminal intron of the thymidylate synthase (TS) RNA and may downregulate TS expression. [provided by RefSeq, Aug 2017]

基因名:ENOSF1
别名:RTS,FUCD,TYMSAS
基因ID:55556
Chromosome:
(GRCh37)
18 Start: 670324 End: 712662 Strand: 
信号通路:  
ENOSF1 基因突变与药物