| 基因名 | 疾病 | 靶向药 | 化疗药 | 基因突变 | 临床解释 |
|---|---|---|---|---|---|
| IDH1 | 急性髓性白血病,间变性少突胶质瘤,星形细胞瘤,脑胶质瘤,神经节胶质瘤,多形胶质母细胞瘤,肝内胆管癌,恶性胶质瘤,骨髓增生异常综合征,胰腺导管腺癌。 | AG-120,AGI-5198,BAY 1436032,贝伐单抗,Bis-2-[5-(phenylacetamide)-1,帕纳替尼/普纳替尼/波纳替尼,4-thiadiazol-2-yl]ethyl Sulfide,Bis-2-(5-phenylacetamido-1,舒尼替尼,4-thiadiazol-2-yl)ethyl Sulfide,西妥昔单抗,达沙替尼,GSK321,Tibsovo,奥拉帕利,替莫唑胺, | 7 | 40 | |
| IDH2 | 急性髓性白血病,星形细胞瘤,脑胶质瘤,多形性胶质母细胞瘤,骨髓增生异常综合征,外周T细胞淋巴瘤 | 恩西地平, | 4 | 18 | |
| IKZF1 | 急性淋巴细胞白血病,小儿B细胞淋巴细胞白血病,前体B淋巴细胞淋巴瘤/白血病 | 2 | 6 | ||
| IGF2 | 卵巢癌,胰腺腺癌,前列腺癌 | 卡巴他赛,Ganitumab,Linsitinib, | 多西他赛, | 1 | 4 |
| IL7R | 小儿B淋巴细胞白血病,T细胞急性淋巴细胞白血病 | 3 | 3 | ||
| IGF1R | 非小细胞肺癌 | 吉非替尼,IGF1R Monoclonal Antibody, | 2 | 2 | |
| IL2RB | 小儿B细胞急性淋巴细胞白血病 | 1 | 1 | ||
| IRS2 | 结直肠癌 | BMS-754807, | 1 | 1 | |
| IGF2R | 0 | 0 | |||
| INPP4B | 0 | 0 | |||
| IKBKE | 0 | 0 | |||
| INHBA | 0 | 0 | |||
| IRF4 | 0 | 0 | |||
| IRF2 | 0 | 0 | |||
| ICOSLG | 0 | 0 | |||
| ID3 | 0 | 0 | |||
| IDO1 | 0 | 0 | |||
| IDO2 | 0 | 0 | |||
| IFNG | 0 | 0 | |||
| IFNGR1 | 0 | 0 | |||
| IGF1 | 0 | 0 | |||
| IKBKB | 0 | 0 | |||
| IL10 | 0 | 0 | |||
| IL6 | 0 | 0 | |||
| IL6R | 0 | 0 | |||
| IL6ST | 0 | 0 | |||
| INHA | 0 | 0 | |||
| INPP4A | 0 | 0 | |||
| INPPL1 | 0 | 0 | |||
| INSR | 0 | 0 | |||
| ITK | 0 | 0 | |||
| ITPA | 0 | 0 | |||
| Iars | 0 | 0 | |||
| Ick | 0 | 0 | |||
| ID2 | 0 | 0 | |||
| IFITM1 | 0 | 0 | |||
| IFITM3 | 0 | 0 | |||
| IFNAR1 | 0 | 0 | |||
| IFNAR2 | 0 | 0 | |||
| IFNGR2 | 0 | 0 | |||
| IFNL3 | 0 | 0 | |||
| IGFL3 | 0 | 0 | |||
| IGLL5 | 0 | 0 | |||
| IGSF10 | 0 | 0 | |||
| IKZF2 | 0 | 0 | |||
| IKZF3 | 0 | 0 | |||
| IL1RAPL1 | 0 | 0 | |||
| IL21R | 0 | 0 | |||
| IMPG1 | 0 | 0 | |||
| ING1 | 0 | 0 | |||
| INPP5D | 0 | 0 | |||
| INSRR | 0 | 0 | |||
| IP6K1 | 0 | 0 | |||
| IPO7 | 0 | 0 | |||
| IQCJ | 0 | 0 | |||
| IRAK1 | 0 | 0 | |||
| IRF1 | 0 | 0 | |||
| IRF6 | 0 | 0 | |||
| IRF8 | 0 | 0 | |||
| IRS1 | 0 | 0 | |||
| ITGAL | 0 | 0 | |||
| ITGB2 | 0 | 0 | |||
| ITGB3 | 0 | 0 | |||
| ITPR2 | 0 | 0 | |||
| ITSN1 | 0 | 0 |
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