| 基因名 | 疾病 | 靶向药 | 化疗药 | 基因突变 | 临床解释 |
|---|---|---|---|---|---|
| DNMT3A | 急性白血病,急性髓系白血病,癌症,骨髓增生异常综合征,T细胞急性淋巴细胞白血病 | 阿特朱单抗，阿替利珠单抗,Decitabine,纳武单抗（纳武利尤单抗）,派姆单抗（帕博利珠单抗）, | 柔红霉素,伊达比星, | 4 | 37 |
| DICER1 | 腺型卵巢卵黄囊肿瘤,恶性舍托利-莱迪格细胞瘤,卵巢癌,卵巢颗粒细胞瘤,胸膜肺母细胞瘤 | 12 | 18 | ||
| DDR2 | 非小细胞肺癌 | 达沙替尼,厄洛替尼, | 7 | 7 | |
| DDIT3 | 黏液样脂肪肉瘤 | NVP-AEW541, | 2 | 3 | |
| DPYD | 癌症 | 卡培他滨, | 氟尿嘧啶,氟特嗪, | 3 | 3 |
| DUX4 | 急性淋巴细胞白血病,小儿B细胞急性淋巴细胞白血病 | 2 | 3 | ||
| DNMT1 | 胃腺癌,卵巢癌 | Decitabine, | 顺铂, | 1 | 2 |
| DROSHA | 癌症,肾威尔姆斯肿瘤 | 2 | 2 | ||
| DCC | 结直肠癌 | 1 | 1 | ||
| DEFA1 | 前列腺癌 | 多西他赛, | 1 | 1 | |
| DUSP6 | 癌症 | 曲美替尼, | 1 | 1 | |
| DEK | 头颈癌 | 派姆单抗（帕博利珠单抗）, | 1 | 1 | |
| DLL3 | 小细胞肺癌 | Rova-T, | 1 | 1 | |
| DKK1 | 结直肠癌 | L-Folinic Acid, | 氟尿嘧啶,伊立替康,奥沙利铂, | 1 | 1 |
| DGKH | 小儿B细胞急性淋巴细胞白血病 | 1 | 1 | ||
| DDX41 | 血液癌 | 1 | 1 | ||
| DDX43 | 葡萄膜黑色素瘤 | PD0325901,司美替尼,曲美替尼, | 1 | 1 | |
| DAXX | 0 | 0 | |||
| DHFR | 0 | 0 | |||
| DOT1L | 0 | 0 | |||
| DCUN1D1 | 0 | 0 | |||
| DDB2 | 0 | 0 | |||
| DDR1 | 0 | 0 | |||
| DDX3X | 0 | 0 | |||
| DIS3 | 0 | 0 | |||
| DIS3L2 | 0 | 0 | |||
| DNAJB1 | 0 | 0 | |||
| DNMT3B | 0 | 0 | |||
| DPP6 | 0 | 0 | |||
| DYNC2H1 | 0 | 0 | |||
| DAPK1 | 0 | 0 | |||
| DBT | 0 | 0 | |||
| DCAF12L1 | 0 | 0 | |||
| DCAF12L2 | 0 | 0 | |||
| DCAF4L2 | 0 | 0 | |||
| DCBLD1 | 0 | 0 | |||
| DCK | 0 | 0 | |||
| DCLRE1C | 0 | 0 | |||
| DDB1 | 0 | 0 | |||
| DDX5 | 0 | 0 | |||
| DENND1A | 0 | 0 | |||
| DEPDC5 | 0 | 0 | |||
| DHX35 | 0 | 0 | |||
| DHX9 | 0 | 0 | |||
| DIAPH1 | 0 | 0 | |||
| DIRAS3 | 0 | 0 | |||
| DLAT | 0 | 0 | |||
| DLC1 | 0 | 0 | |||
| DMC1 | 0 | 0 | |||
| DMD | 0 | 0 | |||
| DNAH1 | 0 | 0 | |||
| DNAH6 | 0 | 0 | |||
| DNAJC11 | 0 | 0 | |||
| DNAJC19 | 0 | 0 | |||
| DOCK11 | 0 | 0 | |||
| DOCK2 | 0 | 0 | |||
| DTX1 | 0 | 0 | |||
| DUT | 0 | 0 | |||
| DNM2 | 0 | 0 | |||
| DNTT | 0 | 0 | |||
| DOCK7 | 0 | 0 | |||
| DRGX | 0 | 0 | |||
| DSCAM | 0 | 0 | |||
| DUSP2 | 0 | 0 | |||
| DUSP22 | 0 | 0 | |||
| DUSP27 | 0 | 0 | |||
| DUSP4 | 0 | 0 | |||
| DYSF | 0 | 0 |
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